The Great London:
Anthropology

  • Breaking News: Neanderthals killed off by diseases from modern humans, claims study

    Breaking News: Neanderthals killed off by diseases from modern humans, claims study

    Modern humans have been blamed for killing off the Neanderthals by out competing them, breeding with them and even outright murdering them.

    Neanderthals killed off by diseases from modern humans, claims study
    Neanderthals may have succumbed to infectious diseases carried to Europe by 
    modern humans as they migrated out of Africa [Credit: George Gillard]

    But new research suggests it may actually have been infectious diseases carried by our modern ancestors as they migrated out of Africa that finished them off.

    Scientists studying the latest genetic, fossil and archaeological evidence claim that Neanderthals suffered from a wide range of diseases that still plague us today.

    They have found evidence that suggests our prehistoric cousins would have been infected by diseases such as tuberculosis, typhoid, whooping cough, encephalitis and the common cold.

    But anthropologists from Cambridge University and Oxford Brookes University say that new diseases carried by modern humans may have led to the downfall of Neanderthals.

    They speculate that pathogens like Heliocbacter pylori, the bacteria that causes stomach ulcers, were brought to Europe by modern humans from Africa and may have infected Neanderthals, who would have been unable to fight off these new diseases.

    However, Neandethals may have also helped modern humans by passing on slivers of immunity against some diseases to our ancestors when they interbred.

    Dr Simon Underdown, a principal lecturer in anthropology at Oxford Brookes University and co-author of the study, said: 'As Neanderthal populations became more isolated they developed very small gene pools and this would have impacted their ability to fight off disease.

    'When Homo sapiens came out of Africa they brought diseases with them.

    'We know that Neanderthals were actually much more advanced than they have been given credit for and we even interbred with them.

    'Perhaps the only difference was that we were able to cope with these diseases but Neanderthals could not.'

    The findings add to a growing body of evidence that Neanderthals were not as different from modern humans as was originally thought.

    Recent discoveries have suggested that rather than being brutish cavemen, Neanderthals had sophisticated culture, were master tool makers and may even have had their own language.

    The new study suggests that Neanderthals also suffered from many of the same afflictions and complaints that modern humans experience.

    Indeed, there is some evidence from caves that early humans may have burned their bedding in a bid to rid themselves of infestations of lice or bed bugs.

    Dr Underdown and his colleague Dr Charlotte Houldcroft, a researcher in infectious diseases at Cambridge University and University College London, analysed recent genetic studies on Neanderthals and other early humans.

    They also examined recent genetic research on common human pathogens that have aimed to trace their origins and combined it with fossil and archaeological evidence.

    Most evidence from the fossil record suggest that Neanderthals tended to suffer traumatic injuries as a result of their hunter gatherer lifestyle, but there are also signs of inflammation and infection.

    Their study, which is published on the open source database bioRxiv, contradicts the common view that infectious diseases only really became a problem for humans in the Holocene about 11,000 years ago when humans began living in dense settlements and farming livestock.

    Instead, they say many of the diseases we see around us today were common during the pleistocene when Neanderthals dominated much of Europe and Asia between 250,000 and 45,000 years ago, when they disappeared.

    They say pathogens like TB, typhoid and Crimean fever that were thought to be zoonoses caught from herd animals may have actually originated in humans and were only passed to animals during the rise of farming around 8,000 years ago.

    Genetic sequencing of Neanderthal and Denisovan - another early human ancestor - DNA has shown that modern humans have inherited a number of genes from these extinct species.

    These include genes that provide immunity to viral infections such as tick-borne encephalitis.

    Dr Underdown said this virus would probably have been common in the forested areas of northern Europe that Neanderthals inhabited and so immunity would have been an advantage.

    Other genes found in modern Papua New Guineans that are involved in the immune response against viruses like dengue and influenza may have come from Neanderthals.

    Analysis of ancient DNA has also shown that Neanderthals carried genes that would have protected them against bacterial blood poisoning, or sepsis.

    Dr Underdown said: 'There are genetic signals in the Neanderthal genome that suggest quite clearly that they were exposed to these types of diseases but also developed some resistance to them.

    'It had been thought that many of these diseases began infecting humans with the population increases that came with domestication of animals and permanent settlements.

    'Be here we have got Neanderthals being infected by these diseases long before those developments.'

    Author: Richard Gray | Source: Daily Mail Online [April 03, 2015]

  • Chanel Islands: Jersey was a must-see tourist destination for Neanderthals for over 100,000 years

    Chanel Islands: Jersey was a must-see tourist destination for Neanderthals for over 100,000 years

    New research led by the University of Southampton shows Neanderthals kept coming back to a coastal cave site in Jersey from at least 180,000 years ago until around 40,000 years ago.

    Jersey was a must-see tourist destination for Neanderthals for over 100,000 years
    Aerial photo of La Cotte de St Brelade [Credit: Dr Sarah Duffy]

    As part of a re-examination of La Cotte de St Brelade and its surrounding landscape, archaeologists from Southampton, together with experts from three other universities and the British Museum, have taken a fresh look at artefacts and mammoth bones originally excavated from within the site's granite cliffs in the 1970s. Their findings are published in the >journal Antiquity.

    The researchers matched types of stone raw material used to make tools to detailed mapping of the geology of the sea bed, and studied in detail how they were made, carried and modified. This helped reconstruct a picture of what resources were available to Neanderthals over tens of thousands of years -- and where they were travelling from.

    Lead author Dr Andy Shaw of the Centre for the Archaeology of Human Origins (CAHO) at the University of Southampton said: "La Cotte seems to have been a special place for Neanderthals. They kept making deliberate journeys to reach the site over many, many generations. We can use the stone tools they left behind to map how they were moving through landscapes, which are now beneath the English Channel. 180,000 years ago, as ice caps expanded and temperatures plummeted, they would have been exploiting a huge offshore area, inaccessible to us today."

    Previous research focussed on particular levels in the site where mammoth bones are concentrated, but this new study took a longer-term perspective, looking at how Neanderthals used it and explored the surrounding landscape for over 100,000 years.

    Jersey was a must-see tourist destination for Neanderthals for over 100,000 years
    Archaeologists at La Cotte de St Brelade [Credit: Dr Sarah Duffy]

    The team, including academics from the British Museum, University College London (UCL) and the University of Wales found that Neanderthals kept coming back to this particular place, despite globally significant changes in climate and landscape. During glacial phases (Ice Ages), they travelled to the site over cold, open landscapes, now submerged under the sea. They kept visiting as the climate warmed up and Jersey became a striking highpoint in a wide coastal plain connected to France.

    Dr Beccy Scott of the British Museum added: "We're really interested in how this site became 'persistent' in the minds of early Neanderthals. You can almost see hints of early mapping in the way they are travelling to it again and again, or certainly an understanding of their geography. But specifically what drew them to Jersey so often is harder to tease out. It might have been that the whole Island was highly visible from a long way off -- like a waymarker -- or people might have remembered that shelter could be found there, and passed that knowledge on."

    Paper author Dr Matt Pope, of the Institute of Archaeology at UCL, agrees: "La Cotte de St Brelade is probably the most important Neanderthal site in northern Europe and could be one of the last known places that Neanderthals survived in the region. It was certainly as important to them as it is to us, as we try and understand how they thrived and survived for 200,000 years.

    "With new technology we have been able to reconstruct the environment of the La Cotte Neanderthals in a way earlier researchers couldn't. Our project has really put the Neanderthal back into the landscape, but emphasised how significant the changes in climate and landscape have been since then."

    Project leader Professor Clive Gamble, of CAHO at the University of Southampton, comments: "Jersey is an island that endures, summed up by the granite cliffs of St Brelade's Bay. The elements which led to Neanderthals coming back for so many thousands of years shows how this persistence is deep rooted in Jersey's past. Our project has shown that more unites the past with the present than separates. We are not the only humans to have coped successfully with major environmental changes. Let's hope we are not the last."

    The team's work was undertaken as part of the 'Crossing the Threshold' project led by Professor Clive Gamble and Dr John McNabb at the University of Southampton, together with UCL and the British Museum. The research was funded by the Arts and Humanities Research Council and looks at major changes in how early humans used places from 400,000 years ago.

    Source: University of Southampton [December 12, 2016]

  • Forensics: Five things you can learn from a Roman skeleton

    Forensics: Five things you can learn from a Roman skeleton

    The stories of Roman lives are written their bones: diet, disease, childbirth and trauma all leave their mark. Individual skeletons can tell rich tales, but the fullest information comes from large groups, when we can look at populations. So what can we learn about about a Roman community from their skeletons?

    Five things you can learn from a Roman skeleton
    The stories of Roman lives are written their bones: Roman skeleton found on
     at York University campus [Credit: University of York/PA]

    Whether they were a slave

    Slavery was ubiquitous in the Roman world, and some of its agonies are preserved on skeletons: those working in and living near Roman mines in Jordan were exposed to lead and copper at levels that would have been toxic, and caused a range of illnesses. The remains of people who were likely to have been slaves have also been found still wearing iron shackles, for instance in a subterranean room of a villa in Pompeii, and near the silver mines of Laurion in Roman-era Greece.

    Whether they played sports

    Among the human remains from ancient Herculaneum, which was destroyed by the eruption of Vesuvius at the same time as Pompeii, were a possible boxer, with typical fractures to his hands and nose, and a javelin-thrower whose bones reveal the same elbow problems experienced by modern athletes.

    How they died, who they loved

    At Dura-Europos in Syria, remains of Roman and Sasanian troops trapped in a siege mine beneath the walls of the ancient city reveal the brutal and violent reality of ancient conflict, including gas warfare. In the nearby cemetery, families were buried together in underground tombs, with women and children placed together.

    Five things you can learn from a Roman skeleton
    A well preserved Roman skeleton from the 2nd-4th century, found in a lead coffin 
    near Aldborough, North Yorkshire [Credit: Christopher Thomond/Guardian]

    Where people came from

    Even places like Roman Britain were diverse. Scientific methods (such as isotope analysis), as well as the study of graves and grave goods (the objects buried with a body) can tell us where a person was likely to have come from, or where they had links to. For instance, work on the cemeteries of Roman York has shown that people buried there came from other places in Britain, and much further afield in Europe, the Middle East and North Africa.

    The extent of childhood illnesses

    In the Roman world, children often didn’t make it to adulthood. Roman cemeteries such as Poundbury in Dorset include many children with rickets, scurvy and anaemia – survival rates were staggeringly low by modern Western standards. Infant and early childhood mortality was high in the Roman period, with 45% of children unlikely to survive past five years of age.

    So we can learn a lot about how a Roman may have lived from her or his remains, but, while skeletons are biological, bodies are cultured and contextual; they can be modified to fit ideals of beauty, status, or gender. Ultimately, Roman skeletons tell us that culture is a significant factor in determining difference: underneath it all, we’re pretty much the same collection of 206 interlocking parts.

    Dr Jen Baird and Dr Tim Reynolds from the Department of History, Classics and Archaeology, Birkbeck College, University of London, will be talking in depth about Roman skeletons at a Guardian Live/Birkbeck event on 21 November.

    Authors: Dr Jen Baird and Dr Tim Reynolds | Source: The Guardian [November 14, 2015]

  • Human Evolution: Monkeys are seen making stone flakes so humans are 'not unique' after all

    Human Evolution: Monkeys are seen making stone flakes so humans are 'not unique' after all

    Researchers have observed wild-bearded capuchin monkeys in Brazil deliberately break stones, unintentionally creating flakes that share many of the characteristics of those produced by early Stone Age hominins. The difference is that the capuchins' flakes are not intentional tools for cutting and scraping, but seem to be the by-product of hammering or 'percussive behaviour' that the monkeys engage in to extract minerals or lichen from the stones.

    Monkeys are seen making stone flakes so humans are 'not unique' after all
    Wild-bearded capuchin monkey in Serra da Capivara National Park, Brazil, unintentionally creating
     fractured flakes and cores [Credit: Michael Haslam/ Primate Archaeology Group]

    In a paper, >published in Nature, the research team says this finding is significant because archaeologists had always understood that the production of multiple stone flakes with characteristics such as conchoidal fractures and sharp cutting edges was a behaviour unique to hominins. The paper suggests that scholars may have to refine their criteria for identifying intentionally produced early stone flakes made by hominins, given capuchins have been observed unintentionally making similar tools.

    The research is authored by researchers from the University of Oxford, University College London and University of Sao Paulo in Brazil. The team observed individual monkeys in Serra da Capivara National Park unintentionally creating fractured flakes and cores. While hominins made stone flake tools for cutting and butchery tasks, the researchers admit that it is unclear why monkeys perform this behaviour. They suggest that the capuchins may be trying to extract powdered silicon (known to be an essential trace nutrient) or to remove lichen for some as yet unknown medicinal purpose. At no point did the monkeys try to cut or scrape using the flakes, says the study.

    Lead author Dr Tomos Proffitt, from the School of Archaeology at the University of Oxford, comments: 'Within the last decade, studies have shown that the use and intentional production of sharp-edged flakes are not necessarily linked to early humans (the genus Homo) who are our direct relatives, but instead were used and produced by a wider range of hominins. However, this study goes one step further in showing that modern primates can produce archaeologically identifiable flakes and cores with features that we thought were unique to hominins.


    'This does not mean that the earliest archaeological material in East Africa was not made by hominins. It does, however, raise interesting questions about the possible ways this stone tool technology developed before the earliest examples in the archaeological record appeared. It also tells us what this stone tool technology might look like. There are important questions too about the uniqueness of early hominin behaviour. These findings challenge previous ideas about the minimum level of cognitive and morphological complexity required to produce numerous conchoidal flakes.'

    The monkeys were observed engaging in 'stone on stone percussion', whereby they individually selected rounded quartzite cobbles and then using one or two hands struck the 'hammer-stone' forcefully and repeatedly on quartzite cobbles embedded in a cliff face. This action crushed the surface and dislodged cobbled stones, and the hand-held 'hammer stones' became unintentionally fractured, leaving an identifiable primate archaeological record. As well as using the active hammer-stone to crush 'passive hammers' (stones embedded in the outcrop), the capuchins were also observed re-using broken hammer-stones as 'fresh' hammers.

    The research team examined 111 fragmented stones collected from the ground immediately after the capuchins had dropped them, as well as from the surface and excavated areas in the site. They gathered complete and broken hammer-stones, complete and fragmented flakes and passive hammers. Around half of the fractured flakes exhibited conchoidal fracture, which is typically associated with the hominin production of flakes.

    Bearded capuchins and some Japanese macaques are known to pound stones directly against each other, but the paper remarks that the capuchins in Serra da Capivara National Park are the only wild primates to be observed doing this for the purpose of damaging the stones.

    Co-author and leader of the Primate Archaeology (Primarch) project Michael Haslam, from the University of Oxford, says: 'Our understanding of the new technologies adopted by our early ancestors helps shape our view of human evolution. The emergence of sharp-edged stone tools that were fashioned and hammered to create a cutting tool was a big part of that story. The fact that we have discovered monkeys can produce the same result does throw a bit of a spanner in the works in our thinking on evolutionary behaviour and how we attribute such artefacts. While humans are not unique in making this technology, the manner in which they used them is still very different to what the monkeys seem capable of.'

    Source: University of Oxford [October 19, 2016]

  • Indigenous Cultures: First estimate of Pygmy population in Central Africa reveals their plight

    Indigenous Cultures: First estimate of Pygmy population in Central Africa reveals their plight

    The forests of Central Africa could be home to up to 920,000 Pygmies, according to researchers from UCL, Manchester Metropolitan University and the University of Malaga, who have conducted the first measured estimate of the population and distribution of these indigenous groups.

    First estimate of Pygmy population in Central Africa reveals their plight
    Pygmy musicians in the Congo Basin, Bottom: Mbendjele girls sharing out harvest 
    [Credit: Jerome Lewis]

    Up until now it has not been possible to determine the numbers and actual geographic ranges of Pygmy communities, because of their location in remote forest areas, mobility, lack of census data, and imprecise and partial sources of information. Pygmy communities live in rainforests across nine countries in Central Africa—an area of some 178 million hectares—where they make up a very small minority of the total population.

    Despite the Pygmies' significance to humanity's cultural diversity as the largest group of active hunter-gatherers in the world, the new study, published in >PLOS ONE, is the first to predict how many Pygmies are likely to be found in the vast expanse of tropical forests in Central Africa. The study maps their distribution and identifies which areas are of ecological importance.

    Dr Jerome Lewis (Hunter-Gatherer Resilience Project, UCL Anthropology), co-author of the paper, said: "This is a very underprivileged and neglected group of people many of whom have already lost their forest land, livelihoods and whose rich cultural traditions are seriously threatened in many regions.

    "Information on their locations and population numbers are crucial for developing appropriate human rights, cultural and land security safeguards for them, as for other indigenous peoples."

    Using a compilation of evidence collected by an unprecedented number of researchers, the authors generated the largest database of Pygmy camp locations throughout their known range.

    As there are no known accurate censuses of Pygmy population the researchers used a statistical method, developed by paper co-author Dr Jesus Olivero (University of Malaga), to forecast the distribution of Pygmies in Central Africa. Based on species distribution models that investigate the relationship between environmental conditions and the distribution of organisms, the study is the first to apply this method to human societies and their cultural diversity.

    Dr Olivero said: "By using tried and tested animal and plant distribution models we hope to promote a greater awareness of the importance of these too often ignored and marginalized groups in this region."

    Professor John Fa (Manchester Metropolitan University), co-author, explained that understanding where and how Pygmy communities live is an important first step in supporting them and safeguarding their rights.

    "It's important for all of the countries involved to come together to help support Pygmies' cultures and human rights to make sure they are respected and understood.

    "At the end of the day, 900,000 people living in small groups in such a vast area can very easily be ignored, leading to their cultural extinction, and given the extraordinary role they have played in the human story since well before antiquity, we don't want that."

    Source: University College London [January 15, 2016]

  • Genetics: Obesity in humans linked to fat gene in prehistoric apes

    Genetics: Obesity in humans linked to fat gene in prehistoric apes

    A genetic mutation in extinct European apes that enabled them to convert fruit sugar into fat could be a cause of the modern obesity epidemic and diabetes, according to scientists. Fossil evidence reveals that apes living around 16 million years ago, in what was then subtropical Europe, began to suffer as global cooling subsequently changed the forest, making the fruit they ate scarce.

    Obesity in humans linked to fat gene in prehistoric apes
    Extinct European apes evolved into today's great apes and the earliest hominids 
    [Credit: Nathan Thompson, Lucille Betti-Nash, and Deming Yang]

    Experts suggest that a mutation in the uricase gene which helps to convert fruit sugar (fructose) occurred around 15 million years ago. This aided apes in adding on fat layers so they could survive famines and harsh winters.

    Persistence of the same mutation in all modern great apes and all modern humans, along with the fossil evidence, suggests that the now extinct European apes evolved into today's great apes and the earliest hominids.

    Scientists have spent decades researching the genetic causes of obesity which is rarely found in other animals – apart from domesticated pets. The latest research focuses on fructose: a sugar which breaks down to form uric acid in the blood, according to a Sunday Times report.

    The Western diet contains so much uric acid that it cannot be removed quickly enough, but triggers liver cells to turn fructose into fat, with the effect of humans adding on extra weight. The uricase mutation predisposes humans to obesity and diabetes in modern times. The results suggest a need to eat and drink much less fructose to fight obesity and prevent its dangerous complications.

    "The gene enables uric acid levels to spike in response to two types of food," wrote Peter Andrews, professor of anthropology at University College London in Scientific American, co-authored with Richard Johnson, a professor of medicine in the US. "Those like beer that produce a lot of uric acid [directly] and those that contain a lot of fructose. These include honey and processed food that are high in table sugar or high-fructose corn syrup. When uric acid spikes we become susceptible to obesity and diabetes."

    Obesity is considered as one of the biggest public health challenges of the century. Statistics show that it is affecting more than 500 million people worldwide. In the US alone, obesity costs at least $200 billion each year.

    This medical condition also contributes to potentially fatal disorders such as cancer, type 2 diabetes and cardiovascular disease.

    Author: Fiona Keating | Source: International Business Times [November 20, 2015]

  • Forensics: Intricate animal and flower tattoos found on Egyptian mummy

    Forensics: Intricate animal and flower tattoos found on Egyptian mummy

    A mummy from ancient Egypt was heavily tattooed with sacred symbols, which may have served to advertise and enhance the religious powers of the woman who received them more than 3,000 years ago.

    Intricate animal and flower tattoos found on Egyptian mummy
    The mummy's tattoos include two seated baboons depicted between a wadjet eye (top row), a symbol of protection 
    [Credit: Anne Austin]

    The newly reported tattoos are the first on a mummy from dynastic Egypt to show actual objects, among them lotus blossoms on the mummy’s hips, cows on her arm and baboons on her neck. Just a few other ancient Egyptian mummies sport tattoos, and those are merely patterns of dots or dashes.

    Especially prominent among the new tattoos are so-called wadjet eyes: possible symbols of protection against evil that adorn the mummy’s neck, shoulders and back.

    “Any angle that you look at this woman, you see a pair of divine eyes looking back at you,” says bioarchaeologist Anne Austin of Stanford University in California, who presented the findings last month at a meeting of the >American Association of Physical Anthropologists.

    Intricate animal and flower tattoos found on Egyptian mummy
    The mummy, found in the ancient village of Deir el-Medina, dates from 1300 to 1070 BC 
    [Credit: Anne Austin]

    Austin noticed the tattoos while examining mummies for the French Institute of Oriental Archaeology, which conducts research at Deir el-Medina, a village once home to the ancient artisans who worked on tombs in the nearby Valley of the Kings. Looking at a headless, armless torso dating from 1300 to 1070 bc, Austin noticed markings on the neck. At first, she thought that they had been painted on, but she soon realized that they were tattoos.

    Hidden history

    Austin knew of tattoos discovered on other mummies using infrared imaging, which peers more deeply into the skin than visible-light imaging. With help from infrared lighting and an infrared sensor, Austin determined that the Deir el-Medina mummy boasts more than 30 tattoos, including some on skin so darkened by the resins used in mummification that they were invisible to the eye. Austin and Cédric Gobeil, director of the French mission at Deir el-Medina, digitally stretched the images to counter distortion from the mummy’s shrunken skin.

    Intricate animal and flower tattoos found on Egyptian mummy
    Because the mummy's skin is distorted and covered in resin, it is difficult to see many tattoos — such as these 
    Hathor cows — with the naked eye [Credit: Anne Austin]

    The tattoos identified so far carry powerful religious significance. Many, such as the cows, are associated with the goddess Hathor, one of the most prominent deities in ancient Egypt. The symbols on the throat and arms may have been intended to give the woman a jolt of magical power as she sang or played music during rituals for Hathor.

    The tattoos may also be a public expression of the woman’s piety, says Emily Teeter, an Egyptologist at the University of Chicago’s Oriental Institute in Illinois. “We didn’t know about this sort of expression before,” Teeter says, adding that she and other Egyptologists were “dumbfounded” when they heard of the finding.

    Some tattoos are more faded than others, so perhaps some were made at different times. This could suggest that the woman’s religious status grew with age, Austin says.

    Intricate animal and flower tattoos found on Egyptian mummy
    Anthropologist Ghada Darwish Al-Khafif uses infrared imaging to examine tattoos on the mummy's back 
    [Credit: Anne Austin]

    Penetrating gaze

    She has already found three more tattooed mummies at Deir el-Medina, and hopes that modern techniques will uncover more elsewhere.

    Even infrared imaging can’t penetrate an intact mummy’s linen binding. But a nineteenth-century penchant for unwrapping mummies could enable the discovery of more tattoos, says Marie Vandenbeusch, a curator at the British Museum in London. Such examples could provide needed evidence “to really pinpoint the use of those tattoos”, she says.

    Austin argues that the scale of the designs, many of them in places out of the woman’s reach, implies that they were more than simple adornment.

    Intricate animal and flower tattoos found on Egyptian mummy
    This enhanced image of the mummy's skin reveals tattoos of two cows 
    [Credit: Anne Austin]

    The application of the tattoos “would’ve been very time consuming, and in some areas of the body, extremely painful”, Austin says. That the woman subjected herself to the needle so often shows “not only her belief in their importance, but others around her as well”.

    Author: Traci Watson | Source: Nature [doi:10.1038/nature.2016.19864] [May 09, 2016]

  • Genetics: Scientists sequence ancient British 'gladiator' genomes from Roman York

    Genetics: Scientists sequence ancient British 'gladiator' genomes from Roman York

    Cutting-edge genome technology in Trinity College Dublin has cast more light on a mystery that has perplexed archaeologists for more than a decade. The origins of a set of Roman-age decapitated bodies, found by York Archaeological Trust at Driffield Terrace in the city, have been explored, revealing a Middle Eastern body alongside native British.

    Scientists sequence ancient British 'gladiator' genomes from Roman York
    One of the skeletons excavated by York Archaeological Trust at Driffield Terrace
    [Credit: York Archaeological Trust]

    Archaeologists have speculated that the skeletons belonged to gladiators, although they could also have been soldiers or criminals. Several suffered perimortem decapitation and were all of a similar age – under 45 years old. Their skulls were buried with the body, although not positioned consistently – some were on the chest, some within the legs, and others at the feet.

    Although examining the skeletons revealed much about the life they lived – including childhood deprivation and injuries consistent with battle trauma – it was not until genomic analysis by a team from Trinity College Dublin, led by Professor of Population Genetics, Dan Bradley, that archaeologists could start to piece together the origins of the men.

    The Trinity College team recently published the first prehistoric Irish genomes and this analysis by Trinity PhD Researcher, Rui Martiniano, also breaks new ground as it represents the first genome analysis of ancient Britons.

    From the skeletons of more than 80 individuals, Dr Gundula Muldner of the University of Reading, Dr Janet Montgomery of the University of Durham and Malin Holst and Anwen Caffel of York Osteoarchaeology selected seven for whole genome analyses. Despite variation in isotope levels which suggested some of the 80 individuals lived their early lives outside Britain, most of those sampled had genomes similar to an earlier Iron Age woman from Melton, East Yorkshire. The poor childhood health of these men suggests that they were locals who endured childhood stress, but their robust skeletons and healed trauma, suggest that they were used to wielding weapons.

    Scientists sequence ancient British 'gladiator' genomes from Roman York
    The Roman-age skeletons from Driffield Terrace laid out in York's Guildhall 
    [Credit: York Archaeological Trust]

    The nearest modern descendants of the Roman British men sampled live not in Yorkshire, but in Wales. A man from a Christian Anglo-Saxon cemetery in the village of Norton, Teesside, has genes more closely aligned to modern East Anglia and Dutch individuals and highlights the impact of later migrations upon the genetic makeup of the earlier Roman British inhabitants.

    However, one of the decapitated Romans had a very different story, of Middle Eastern origin he grew up in the region of modern day Palestine, Jordan or Syria before migrating to this region and meeting his death in York.

    "Archaeology and osteoarchaeology can tell us a certain amount about the skeletons, but this new genomic and isotopic research can not only tell us about the body we see, but about its origins, and that is a huge step forward in understanding populations, migration patterns and how people moved around the ancient world," says Christine McDonnell, Head of Curatorial and Archive Services for York Archaeological Trust.

    "This hugely exciting, pioneering work will become the new standard for understanding the origins of skeletons in the future, and as the field grows, and costs of undertaking this kind of investigation fall, we may be able to refine our knowledge of exactly where the bodies were born to a much smaller region. That is a remarkable advance."

    Scientists sequence ancient British 'gladiator' genomes from Roman York
    The Roman skeletons were found at Driffield Terrace in York with their skulls placed between their legs,
     at their feet or on their chests [Credit: York Archaeological Trust]

    As well as Trinity College Dublin, the multi-disciplinary scientific analysis involved scientists from the University of York and The York Archaeological Trust, as well as the universities of Durham, Reading and Sheffield, University College London and the University Medical Centre in Utrecht. The research also included experts from York Osteoarchaeology Ltd, City of York Council and the Natural History Museum.

    The Roman skeletons sampled were all male, under 45 years old and most had evidence of decapitation. They were taller than average for Roman Britain and displayed evidence of significant trauma potentially related to interpersonal violence. All but one would have had brown eyes and black or brown hair but one had distinctive blue eyes and blond hair similar to the single Anglo-Saxon individual.

    The demographic profile of the York skeletons resembles the population structure in a Roman burial ground believed to be for gladiators at Ephesus. But the evidence could also fit with a military context—the Roman army had a minimum recruitment height and fallen soldiers would match the age profile of the York cemetery.

    Professor Dan Bradley, Trinity, said: "Whichever the identity of the enigmatic headless Romans from York, our sample of the genomes of seven of them, when combined with isotopic evidence, indicate six to be of British origin and one to have origins in the Middle East. It confirms the cosmopolitan character of the Roman Empire even at its most northerly extent."

    PhD Researcher and lead author, Rui Martiniano, Trinity, said: "This is the first refined genomic evidence for far-reaching ancient mobility and also the first snapshot of British genomes in the early centuries AD, indicating continuity with an Iron Age sample before the migrations of the Anglo-Saxon period."

    Professor Matthew Collins, of the BioArCh research facility in the Department of Archaeology at York, who co-ordinated the report on the research, "These genomes give the first snapshot of British genomes in the early centuries AD, showing continuity with the earlier Iron Age and evidence of migrations in the Anglo-Saxon period."

    The paper is published in >Nature Communications.

    Source: Trinity College Dublin [January 20, 2016]

  • Genetics: DNA analysis reveals Roman London was a multi-ethnic melting pot

    Genetics: DNA analysis reveals Roman London was a multi-ethnic melting pot

    A DNA analysis of four ancient Roman skeletons found in London shows the first inhabitants of the city were a multi-ethnic mix similar to contemporary Londoners, the Museum of London said on Monday.

    DNA analysis reveals Roman London was a multi-ethnic melting pot
    The displayed skeleton of "The Harper Road Woman", one of four 
    ancient Roman skeletons that have undergone DNA analysis 
    [Credit: Museum of London/AFP]

    Two of the skeletons were of people born outside Britain -- one of a man linked genealogically to eastern Europe and the Near East, the other of a teenage girl with blue eyes from north Africa.

    The injuries to the man's skull suggest that he may have been killed in the city's amphitheatre before his head was dumped into an open pit.

    Both the man and the girl were suffering from periodontal disease, a type of gum disease.

    The other two skeletons of people believed to have been born in Britain were of a woman with maternal ancestry from northern Europe and of a man also with links through his mother to Europe or north Africa.

    "We have always understood that Roman London was a culturally diverse place and now science is giving us certainty," said Caroline McDonald, senior curator of Roman London at the museum.

    "People born in Londinium lived alongside people from across the Roman Empire exchanging ideas and cultures, much like the London we know today," she said.

    The museum said in a statement that this was "the first multidisciplinary study of the inhabitants of a city anywhere in the Roman Empire".

    The Romans founded Britain's capital city in the middle of the first century AD, under the emperor Claudius.

    Britain's University of Durham researched stable isotopes from tooth enamel to determine migration patterns.

    A tooth from each skeleton was also sent to McMaster University in Canada for DNA analysis that established the hair and eye colour of each individual and identified the diseases they were suffering from.

    McMaster University also examined the mitochondrial DNA (mtDNA) to identify maternal ancestry.

    The exhibition of the four skeletons, entitled "Written in Bone", opens on Friday.

    Source: AFP [November 24, 2015]

  • Forensics: Slavery carried bilharzia parasites from West Africa to the Caribbean

    Forensics: Slavery carried bilharzia parasites from West Africa to the Caribbean

    Scientists used the full DNA sequences of Schistosoma mansoni parasites from Africa and the French Caribbean to discover the fluke's origins, map its historic transmission and identify the secrets of its success. Their findings, published in Scientific Reports, show how the global slave trade transported the disease from Senegal and Cameroon to Guadeloupe. Further genomic comparison with a closely related schistosome species that infects rodents reveals how the parasite has adapted to infecting human beings.

    Slavery carried bilharzia parasites from West Africa to the Caribbean
    The bilharzia-causing parasite, Schistosoma mansoni,  first infected humans as they fished
     in lakes in East Africa and was spread, first to West Africa and then to the New World, 
    by slave traders in 16th-19th Centuries, genomics reveals 
    [Credit: Wellcome Trust Sanger Institute]

    Schistosoma mansoni is a blood fluke (flatworm) that infects more than 250 million people worldwide and causes more than 11,000 deaths each year. Six years ago the Sanger Institute published the parasite's first full DNA sequence (genome); this latest study used that 'genetic map' to construct and compare the genomes of S. mansoni parasites gathered from across Africa and the New World, the majority of which were held at the Schistosomiasis Collection in the Natural History Museum, London.

    By analysing the differences between the human-infecting S. mansoni and its close relative, the rodent-infecting S. rodhaini, the scientists calculated that the two species evolved from a common ancestor approximately 107,000 to 148,000 years ago in East Africa. This finding suggests that the species is much 'younger' than previously thought.

    "The timing of the separation of the two species coincidences with the first archaeological evidence of fishing in Africa," explains Thomas Crellen, first author of the study from Imperial College London, the Sanger Institute and the Royal Veterinary College London. "The parasite develops in freshwater and infects people by burrowing through their skin. The introduction of fishing would have meant that people spent more time in the water, greatly increasing their chances of being infected."

    Analysing the differences between genomes from different locations also revealed the darker side of human history.

    "Comparing the S. mansoni genomes suggests that flukes in West Africa split from their Caribbean counterparts at some point between 1117AD and 1742AD, which overlaps with the time of the 16th-19th Century Atlantic Slave Trade," says Professor Joanne Webster from Imperial College London and the Royal Veterinary College. "During this period more than 22,000 African people were transported from West Africa to Guadeloupe by French slave ships, and the fluke was carried with them."

    Comparing the genomes of S. mansoni with S. rodhaini also revealed the genetic variations that have been positively selected over time in the human-infecting fluke and have been "fixed" into its DNA. It is likely that these variations are the evolutionary adaptations that have occurred to enable the fluke to successfully tunnel into, and thrive within, human beings.

    "When we looked for the differences between human-infecting S. mansoni DNA and its rodent infecting cousin S. rodhaini, we found two important variations. We found that changes to two genes in S. mansoni's DNA -- VAL21 and an elastase gene -appear to be important in allowing the fluke to enter and live in humans," says Dr James Cotton, senior author of the study from the Sanger Institute. "VAL genes produce proteins that cause allergic responses, so it is possible that the variation in VAL21 helps the fluke to hide from our immune systems. The elastase gene helps the parasite to burrow in to the body, by breaking down elastin -- a major component of human skin."

    It is hoped that exploring the genetic makeup of the fluke it will be possible to discover more about the processes the parasite relies on to infect humans and offer new opportunities to develop preventive and therapeutic interventions.

    Source: Wellcome Trust Sanger Institute [February 17, 2016]

  • Indigenous Cultures: Brazil land grab threatens isolated tribes: activists

    Indigenous Cultures: Brazil land grab threatens isolated tribes: activists

    The worst land grab in decades in the Brazilian Amazon is threatening the survival of isolated tribes that have no contact with the outside world, a rights group said Wednesday.

    Brazil land grab threatens isolated tribes: activists
    Ranchers and settlers in the remotest reaches of northwestern Brazil are voraciously cutting down rainforest 
    to farm crops, encroaching on the ancestral lands of three uncontacted groups, said Survival International 
    [Credit: AFP/Yasuyoshi Chiba]

    Ranchers and settlers in the remotest reaches of northwestern Brazil are voraciously cutting down rainforest to farm crops, encroaching on the ancestral lands of three uncontacted groups, said Survival International.

    The land grab is also threatening another tribe, the Uru Eu Wau Wau, or "Harpy Eagle" people, that has only limited contact with the outside world, said the London-based group.

    Warning the groups face "annihilation," it accused local politicians in the state of Rondonia of backing the deforestation, even though the area is officially designated as an indigenous reserve and sits within a national park, Pacaas Novas.

    Because isolated peoples' immune systems have never been exposed to the outside world's diseases, the land grab risks causing devastating outbreaks, Survival said.

    "Around the world, industrialized society is stealing tribal lands in the pursuit of profit. What's happening in Brazil is simply a continuation of the invasion and genocide which characterized the European colonization of the Americas," said the group's director, Stephen Corry.

    The organization quoted a letter the Harpy Eagle tribe sent to Brazilian police, in which they call the land grab "extremely serious."

    "We are very worried because the invasions are close to our villages and putting the lives of women, old people, children and men at risk," said the letter.

    Experts estimate between 50 and 90 percent of the populations of Brazil's isolated tribes were wiped out when the government initiated contact with them in the 1970s and 80s—official policy at the time.

    Today, the government tries to avoid any contact with isolated peoples, in order to protect them.

    Brazil is home to some 900,000 indigenous people from 305 different ethnic groups.

    Source: AFP [October 27, 2016]

  • Early Humans: Modern humans out of Africa sooner than thought

    Early Humans: Modern humans out of Africa sooner than thought

    Human teeth discovered in southern China provide evidence that our species left the African continent up to 70,000 years earlier than prevailing theories suggest, a study published on Wednesday said.

    Modern humans out of Africa sooner than thought
    47 human teeth found in the Fuyan Cave, Daoxian, in southern China 
    [Credit: AFP/S. Xing and X-J. Wu]

    Homo sapiens reached present-day China 80,000-120,000 years ago, according to the study, which could redraw the migration map for modern humans.

    "The model that is generally accepted is that modern humans left Africa only 50,000 years ago," said Maria Martinon-Torres, a researcher at University College London and a co-author of the study.

    "In this case, we are saying the H. sapiens is out of Africa much earlier," she told the peer-reviewed journal Nature, which published the study.

    While the route they travelled remains unknown, previous research suggests the most likely path out of East Africa to east Asia was across the Arabian Peninsula and the Middle East.

    The findings also mean that the first truly modern humans -- thought to have emerged in east Africa some 200,000 years ago -- landed in China well before they went to Europe.

    There is no evidence to suggest that H. sapiens entered the European continent earlier than 45,000 years ago, at least 40,000 years after they showed up in present-day China.

    The 47 teeth exhumed from a knee-deep layer of grey, sandy clay inside the Fuyan Cave near the town of Daoxian closely resemble the dental gear of "contemporary humans," according to the study.

    They could only have come from a population that migrated from Africa, rather than one that evolved from an another species of early man such as the extinct Homo erectus, the authors said.

    The scientists also unearthed the remains of some 38 mammals, including specimens of five extinct species, one of them a giant panda larger than those in existence today.

    Modern humans out of Africa sooner than thought
    The location and interior views of the Fuyan Cave, with dating sample (lower left), 
    plan view of the excavation area with stratigraphy layer marked (C) 
    and the spatial relationship of the excavated regions 
    [Credit: AFP/Y-J Cai, X-X Yang, and X-J Wu]

    No tools were found.

    "Judging by the cave environment, it may not have been a living place for humans," lead author Wu Liu from the Chinese Academy of Science in Beijing told AFP.

    The study, published in the journal Nature, also rewrites the timeline of early man in China.

    Up to now, the earliest proof of H. sapiens east of the Arabian Peninsula came from the Tianyuan Cave near Beijing, and dated from no more than 40,000 years ago.

    The new discovery raises questions about why it took so long for H. sapiens to find their way to nearby Europe.

    "Why is it that modern humans -- who were already at the gates -- didn't really get into Europe?", Martinon-Torres asked.

    Wu and colleagues propose two explanations.

    The first is the intimidating presence of Neanderthal man. While this species of early human eventually died out, they were spread across the European continent up until at least some 50,000 years ago.

    "The classic idea is that H. sapiens... took over the Neanderthal empire, but maybe Neanderthals were a kind of ecological barrier, and Europe was too small a place" for both, Martinon-Torres said.

    Modern humans out of Africa sooner than thought
    Human upper teeth found in the Fuyan Cave, Daoxian, 
    in southern China [Credit: AFP/S. Xing and X-J. Wu]

    Another impediment might have been the cold.

    Up until the Ice Age ended 12,000 years ago, ice sheets stretched across a good part of the European continent, a forbidding environment for a new species emerging from the relative warmth of East Africa.

    "H. sapiens originated in or near the tropics, so it makes sense that the species' initial dispersal was eastwards rather than northwards, where winter temperatures rapidly fell below freezing," Robin Dennell of the University of Exeter said in a commentary, also in Nature.

    Martinon-Torres laid out some of the questions to be addressed in future research, using both genetics and fossil records.

    "What are the origins of these populations, and what was their fate? Did they vanish? Could they be the ancestors of later and current populations that entered Europe?"

    She also suggested there might have been "different movements and migrations" out of Africa, not just one.

    Besides the prehistoric panda, called Ailuropoda baconi, the scientists found an extinct species of a giant spotted hyaena.

    An elephant-like creature called Stegodon orientalis and a giant tapir, also present, were species that may have survived into the era when the Chinese had developed writing, some 3500 years ago.

    The cache of teeth nearly went unnoticed, Wu told AFP.

    He and his Chinese colleagues discovered the cave -- and its menagerie of long-deceased animals -- in the 1980s, but had no inkling that it also contained human remains.

    But 25 years later, while revisiting the site, Wu had a hunch.

    "By thinking about the cave environment, we realised that human fossils might be found there," he told AFP by email. "So we started a five-year excavation."

    Author: Marlowe Hood | Source: AFP [October 14, 2015]

  • Forensics: Palaeolithic remains show cannibalistic habits of human ancestors

    Forensics: Palaeolithic remains show cannibalistic habits of human ancestors

    Analysis of ancient cadavers recovered at a famous archaeological site confirm the existence of a sophisticated culture of butchering and carving human remains, according to a team of scientists from the Natural History Museum, University College London, and a number of Spanish universities.

    Palaeolithic remains show cannibalistic habits of human ancestors
    Human skull-cup uncovered in Gough's Cave, Somerset [Credit: The Trustees
     of the Natural History Museum, London]

    Gough's Cave in Somerset was thought to have given up all its secrets when excavations ended in 1992, yet research on human bones from the site has continued in the decades since.

    After its discovery in the 1880s, the site was developed as a show cave and largely emptied of sediment, at times with minimal archaeological supervision.

    The excavations uncovered intensively-processed human bones intermingled with abundant butchered large mammal remains and a diverse range of flint, bone, antler, and ivory artefacts.

    Palaeolithic remains show cannibalistic habits of human ancestors
    Fragments of human skull and mandibles from Gough's Cave [Credit: The Trustees 
    of the Natural History Museum, London]

    New radiocarbon techniques have revealed remains were deposited over a very short period of time, possibly during a series of seasonal occupations, about 14,700 years ago.

    Dr Silvia Bello, from the Natural History Museum's Department of Earth Sciences, lead researcher of the work said, "The human remains have been the subject of several studies. In a previous analysis, we could determine that the cranial remains had been carefully modified to make skull-cups. During this research, however, we've identified a far greater degree of human modification than recorded in earlier. We've found undoubting evidence for defleshing, disarticulation, human chewing, crushing of spongy bone, and the cracking of bones to extract marrow."

    Palaeolithic remains show cannibalistic habits of human ancestors
    Human chewing damage on a rib bone, showing breaks made by saw-teeth (white arrows), 
    dug out furrows (B), and slicing cut marks (C). Scale bar  = 250 μm. 
    [Credit: The Trustees of the Natural History Museum, London]

    The presence of human tooth marks on many of the bones provides incontrovertible evidence for cannibalism, the team found. In a wider context, the treatment of the human corpses and the manufacture and use of skull-cups at Gough's Cave has parallels with other ancient sites in central and western Europe.

    But the new evidence from Gough's Cave suggests that cannibalism during the 'Magdalenian period' was part of a customary mortuary practice that combined intensive processing and consumption of the bodies with the ritual use of skull-cups.

    Simon Parfitt, of University College London, said, "A recurring theme of this period is the remarkable rarity of burials and how commonly we find human remains mixed with occupation waste at many sites. Further analysis along the lines used to study Gough's Cave will help to establish whether the type of ritualistic cannibalism practiced there is a regional ('Creswellian') phenomenon, or a more widespread practice found throughout the Magdalenian world."

    Source: Natural History Museum [April 16, 2015]

  • Breaking News: Complex genetic ancestry of Americans uncovered

    Breaking News: Complex genetic ancestry of Americans uncovered

    By comparing the genes of current-day North and South Americans with African and European populations, an Oxford University study has found the genetic fingerprints of the slave trade and colonization that shaped migrations to the Americas hundreds of years ago.

    Complex genetic ancestry of Americans uncovered
    A 1770 painting showing Spanish, Peruvian and mixed-race people
    [Credit: WikiCommons]

    The study published in Nature Communications found that:

    • While Spaniards provide the majority of European ancestry in continental American Hispanic/Latino populations, the most common European genetic source in African-Americans and Barbadians comes from Great Britain.
    • The Basques, a distinct ethnic group spread across current-day Spain and France, provided a small but distinct genetic contribution to current-day Continental South American populations, including the Maya in Mexico.
    • The Caribbean Islands of Puerto Rico and the Dominican Republic are genetically similar to each other and distinct from the other populations, probably reflecting a different migration pattern between the Caribbean and mainland America.
    • Compared to South Americans, people from Caribbean countries (such as the Barbados) had a larger genetic contribution from Africa.
    • The ancestors of current-day Yoruba people from West Africa (one of the largest African ethnic groups) provided the largest contribution of genes from Africa to all current-day American populations.
    • The proportion of African ancestry varied across the continent, from virtually zero (in the Maya people from Mexico) to 87% in current-day Barbados.
    • South Italy and Sicily also provided a significant European genetic contribution to Colombia and Puerto Rico, in line with the known history of Italian emigrants to the Americas in the late 19th and early 20th century.
    • One of the African-American groups from the USA had French ancestry, in agreement with historical French immigration into the colonial Southern United States.
    • The proportion of genes from European versus African sources varied greatly from individual to individual within recipient populations.

    The team, which also included researchers from UCL (University College London) and the Universita' del Sacro Cuore of Rome, analysed more than 4,000 previously collected DNA samples from 64 different populations, covering multiple locations in Europe, Africa and the Americas. Since migration has generally flowed from Africa and Europe to the Americas over the last few hundred years, the team compared the 'donor' African and European populations with 'recipient' American populations to track where the ancestors of current-day North and South Americans came from.

    'We found that the genetic profile of Americans is much more complex than previously thought,' said study leader Professor Cristian Capelli from the Department of Zoology.

    The research team analysed DNA samples collected from people in Barbados, Columbia, the Dominican Republic, Ecuador, Mexico, Puerto Rico and African-Americans in the USA.

    They used a technique called haplotype-based analysis to compare the pattern of genes in these 'recipient populations' to 'donor populations' in areas where migrants to America came from.

    'We firstly grouped subsets of people in Africa and Europe who were genetically similar and used this fine scale resolution to find which combinations of these clusters resulted in the sort of mixtures that we now see in people across the Americas', said the study's first author, Dr Francesco Montinaro from the Department of Zoology.

    'We can see the huge genetic impact that the slave trade had on American populations and our data match historical records', said study author Dr Garrett Hellenthal from the UCL Genetics Institute, 'The majority of African Americans have ancestry similar to the Yoruba people in West Africa, confirming that most African slaves came from this region. In areas of the Americas historically under Spanish rule, populations also have ancestry related to what is now Senegal and Gambia. Records show that around a third of the slaves sent to Spanish America in the 17th Century came from this region, and we can see the genetic evidence of this in modern Americans really clearly.'

    These genetic findings also uncover previously unknown migration. ‘We found a clear genetic contribution from the Basques in modern-day Maya in Mexico’, said Professor Capelli. ‘This suggests that the Basque also took part in the colonisation of the Americas, coming over either with the Spanish conquistadores or in later waves of migration’.

    'The differences in European ancestry between the Caribbean islands and mainland American population that we found were also previously unknown. It is likely that these differences reflect different patterns of migration between the Caribbean and mainland America.'

    'These results show just how powerful a genetic approach can be when it comes to uncovering hidden patterns of ancestry. We hope to use the same approach to look at other populations with diverse genetic contributions, such as Brazilians,' said Professor Capelli.

    Source: University of Oxford [March 24, 2015]

  • Forensics: New research to shed fresh light on the impact of industrialisation

    Forensics: New research to shed fresh light on the impact of industrialisation

    The Museum of London today announced a ground-breaking research project to explore the effects of industrialisation on Londoners. The research hopes to uncover new clues about the very nature of disease and how it has affected people as Britain has moved into the age of industrialisation.

    New research to shed fresh light on the impact of industrialisation
    Some of London’s most important skeletons will be digitally x-rayed and scanned 
    in a new archaeological investigation linking “man-made” diseases with
     the industrialisation of the city [Credit: © Museum of London]

    The research has been made possible by a City of London Archaeological Trust grant from a bequest made by the late Rosemary Green.

    John Schofield, Secretary of the City of London Archaeological Trust, said: “The City of London Archaeological Trust is very happy that the Rosemary Green bequest is used to gather this cutting-edge data on the signs of industrialisation in the skeletal collections on the Museum of London.”

    Leading the project is Jelena Bekvalac, based at the Museum of London’s Centre for Human Bioarcheology, along with her research team, Gaynor Western and Mark Farmer.

    Jelena Bekvalac, said: “The most tangible evidence we have for the long-term consequences of the industrialisation process upon us is, quite simply, written in our bones. Using the very latest digital technology, we will examine the skeletal remains of over 1,000 adult men and women from industrial-era London in addition to a further 500 skeletons from the medieval metropolis.

    New research to shed fresh light on the impact of industrialisation
    More than 1,000 adult men and women from the industrial revolution period,
     as well as 500 more from the medieval metropolis, will be used in quest to
     find out how the era affected the population at the Museum of London’s 
    Centre for Human Bioarchaeology [Credit: © Museum of London]

    “Modern health trends have seen a shift towards increasing life expectancy but we want to look again at what are often thought of as ‘man-made’ conditions like obesity and cancer. Given today’s more sedentary lifestyles, far removed from the physically active and natural existence of most of our forebears, there are some big questions about the origins of these diseases and how they relate to the modern environment.”

    The research aims to address some of these questions by analysing diseases affecting the human skeleton. The museum will use the latest clinical techniques, including direct digital radiography, CT scanning and 3D modelling, to get a better understanding of what the bones tell us and to assess their change over time. The research aims to examine the influence of the industrial revolution, a pivotal catalyst in the formation of the modern age, on the changing nature of disease – from the medieval and post-medieval periods through to the present day.

    The project offers an exciting opportunity to digitise some of London’s most important skeletal collections, while simultaneously telling a new story about the health of Londoners over time.

    This work will culminate in the creation of an extensive new interactive digital resource that can be explored online. Jelena Bekvalac plans to make an immediate start on the digital scanning. She aims to publish her team’s findings as soon as possible and deliver a series of lectures about the work.

    Source: Museum of London [April 24, 2015]

  • Genetics: Genes for nose shape found

    Genetics: Genes for nose shape found

    Genes that drive the shape of human noses have been identified by a UCL-led study. The four genes mainly affect the width and 'pointiness' of noses which vary greatly between different populations. The new information adds to our understanding of how the human face evolved and may help contribute to forensic DNA technologies that build visual profiles based on an individual's genetic makeup.

    Genes for nose shape found
    Variation between nose shape and the specific genes responsible 
    [Credit: Dr Kaustubh Adhikari, UCL]

    The study, published today in >Nature Communications, analysed a population of over 6,000 people with varied ancestry across Latin America to study the differences in normal facial features and identify the genes which control the shape of the nose and chin.

    The researchers identified five genes which play a role in controlling the shape of specific facial features. DCHS2, RUNX2, GLI3 and PAX1 affect the width and pointiness of the nose and another gene -- EDAR -- affects chin protrusion.

    "Few studies have looked at how normal facial features develop and those that have only looked at European populations, which show less diversity than the group we studied. What we've found are specific genes which influence the shape and size of individual features, which hasn't been seen before.

    "Finding out the role each gene plays helps us to piece together the evolutionary path from Neanderthal to modern humans. It brings us closer to understanding how genes influence the way we look, which is important for forensics applications," said the first author of the report, Dr Kaustubh Adhikari, UCL Cell & Developmental Biology.

    People have different shaped facial features based on their genetic heritage and this is partly due to how the environment influenced the evolution of the human genome. The nose, for example, is important for regulating the temperature and humidity of the air we breathe in so developed different shapes in warmer and cooler climates.

    "It has long been speculated that the shape of the nose reflects the environment in which humans evolved. For example, the comparatively narrower nose of Europeans has been proposed to represent an adaptation to a cold, dry climate. Identifying genes affecting nose shape provides us with new tools to examine this question, as well as the evolution of the face in other species. It may also help us understand what goes wrong in genetic disorders involving facial abnormalities," explained Professor Andrés Ruiz-Linares UCL Biosciences, who led the study.

    The team collected and analysed DNA samples from 6,630 volunteers from the CANDELA cohort recruited in Brazil, Colombia, Chile, Mexico and Peru. After an initial screen, a sample size of 5,958 was used. This group included individuals of mixed European (50%), Native American (45%) and African (5%) ancestry, resulting in a large variation in facial features.

    Both men and women were assessed for 14 different facial features and whole genome analysis identified the genes driving differences in appearance.

    A subgroup of 3,000 individuals had their features assessed using a 3D reconstruction of the face in order to obtain exact measurements of facial features and the results identified the same genes.

    The study identified genes that are involved in bone and cartilage growth and the development of the face. GLI3, DCHS2 and PAX1 are all genes known to drive cartilage growth -- GLI3 gave the strongest signal for controlling the breadth of nostrils, DCHS2 was found to control nose 'pointiness' and PAX1 also influences nostril breadth. RUNX2 which drives bone growth was seen to control nose bridge width.

    The genes GLI3, DCHS2 and RUNX2 are known to show strong signals of recent selection in modern humans compared to archaic humans such as Neanderthals and Denisovans; GLI3 in particular undergoing rapid evolution.

    Source: University College London [May 19, 2016]

  • Genetics: First fine-scale genetic map of the British Isles

    Genetics: First fine-scale genetic map of the British Isles

    Many people in the UK feel a strong sense of regional identity, and it now appears that there may be a scientific basis to this feeling, according to a landmark new study into the genetic makeup of the British Isles.

    First fine-scale genetic map of the British Isles
    Subtle differences in the genes of more than 2,000 people in England, Scotland, Wales 
    and Northern Ireland reveal 17 distinct groups, represented by different symbols 
    and colors on the map [Credit: Stephen Leslie; Contains OS data 
    © Crown copyright and database right 2012; © EuroGeographics
     for some administrative boundaries]

    An international team, led by researchers from the University of Oxford, UCL (University College London) and the Murdoch Childrens Research Institute in Australia, used DNA samples collected from more than 2,000 people to create the first fine-scale genetic map of any country in the world.

    Their findings, published in Nature, show that prior to the mass migrations of the 20th century there was a striking pattern of rich but subtle genetic variation across the UK, with distinct groups of genetically similar individuals clustered together geographically.

    By comparing this information with DNA samples from over 6,000 Europeans, the team was also able to identify clear traces of the population movements into the UK over the past 10,000 years. Their work confirmed, and in many cases shed further light on, known historical migration patterns.

    Key findings

    • There was not a single "Celtic" genetic group. In fact the Celtic parts of the UK (Scotland, Northern Ireland, Wales and Cornwall) are among the most different from each other genetically. For example, the Cornish are much more similar genetically to other English groups than they are to the Welsh or the Scots.
    • There are separate genetic groups in Cornwall and Devon, with a division almost exactly along the modern county boundary.
    • The majority of eastern, central and southern England is made up of a single, relatively homogeneous, genetic group with a significant DNA contribution from Anglo-Saxon migrations (10-40% of total ancestry). This settles a historical controversy in showing that the Anglo-Saxons intermarried with, rather than replaced, the existing populations.
    • The population in Orkney emerged as the most genetically distinct, with 25% of DNA coming from Norwegian ancestors. This shows clearly that the Norse Viking invasion (9th century) did not simply replace the indigenous Orkney population.
    • The Welsh appear more similar to the earliest settlers of Britain after the last ice age than do other people in the UK.
    • There is no obvious genetic signature of the Danish Vikings, who controlled large parts of England ("The Danelaw") from the 9th century.
    • There is genetic evidence of the effect of the Landsker line -- the boundary between English-speaking people in south-west Pembrokeshire (sometimes known as "Little England beyond Wales") and the Welsh speakers in the rest of Wales, which persisted for almost a millennium.
    • The analyses suggest there was a substantial migration across the channel after the original post-ice-age settlers, but before Roman times. DNA from these migrants spread across England, Scotland, and Northern Ireland, but had little impact in Wales.
    • Many of the genetic clusters show similar locations to the tribal groupings and kingdoms around end of the 6th century, after the settlement of the Anglo-Saxons, suggesting these tribes and kingdoms may have maintained a regional identity for many centuries.

    The Wellcome Trust-funded People of the British Isles study analysed the DNA of 2,039 people from rural areas of the UK, whose four grandparents were all born within 80km of each other. Because a quarter of our genome comes from each of our grandparents, the researchers were effectively sampling DNA from these ancestors, allowing a snapshot of UK genetics in the late 19th Century. They also analysed data from 6,209 individuals from 10 (modern) European countries.

    To uncover the extremely subtle genetic differences among these individuals the researchers used cutting-edge statistical techniques, developed by four of the team members. They applied these methods, called fineSTRUCTURE and GLOBETROTTER, to analyse DNA differences at over 500,000 positions within the genome. They then separated the samples into genetically similar individuals, without knowing where in the UK the samples came from. By plotting each person onto a map of the British Isles, using the centre point of their grandparents' birth places, they were able to see how this distribution correlated with their genetic groupings.

    The researchers were then able to "zoom in" to examine the genetic patterns in the UK at levels of increasing resolution. At the broadest scale, the population in Orkney (islands to the north of Scotland) emerged as the most genetically distinct. At the next level, Wales forms a distinct genetic group, followed by a further division between north and south Wales. Then the north of England, Scotland, and Northern Ireland collectively separate from southern England, before Cornwall forms a separate cluster. Scotland and Northern Ireland then separate from northern England. The study eventually focused at the level where the UK was divided into 17 genetically distinct clusters of people.

    Dr Michael Dunn, Head of Genetics & Molecular Sciences at the Wellcome Trust, said: "These researchers have been able to use modern genetic techniques to provide answers to the centuries' old question -- where we come from. Beyond the fascinating insights into our history, this information could prove very useful from a health perspective, as building a picture of population genetics at this scale may in future help us to design better genetic studies to investigate disease."

    Source: Wellcome Trust [March 18, 2015]

  • Indigenous Cultures: Unique social structure of hunter-gatherers explained

    Indigenous Cultures: Unique social structure of hunter-gatherers explained

    Sex equality in residential decision-making explains the unique social structure of hunter-gatherers, a new UCL study reveals.

    Unique social structure of hunter-gatherers explained
    Agta household [Credit: Mark Dyble]

    Previous research has noted the low level of relatedness in hunter-gatherer bands. This is surprising because humans depend on close kin to raise offspring, so generally exhibit a strong preference for living close to parents, siblings and grandparents.

    The new study, published today in Science and funded by the Leverhulme Trust, is the first to demonstrate the relationship between sex equality in residential decision-making and group composition.

    In work conducted over two years, researchers from the Hunter-Gatherer Resilience Project in UCL Anthropology lived among populations of hunter-gatherers in Congo and the Philippines. They collected genealogical data on kinship relations, between-camp mobility and residence patterns by interviewing hundreds of people.

    This information allowed the researchers to understand how individuals in each community they visited were related to each other. Despite living in small communities, these hunter-gatherers were found to be living with a large number of individuals with whom they had no kinship ties.

    The authors constructed a computer model to simulate the process of camp assortment. In the model, individuals populated an empty camp with their close kin - siblings, parents and children.

    When only one sex had influence over this process, as is typically the case in male-dominated pastoral or horticultural societies, camp relatedness was high. However, group relatedness is much lower when both men and women have influence - as is the case among many hunter-gatherer societies, where families tend to alternate between moving to camps where husbands have close kin and camps where wives have close kin.

    First author of the study, Mark Dyble (UCL Anthropology), said: "While previous researchers have noted the low relatedness of hunter-gatherer bands, our work offers an explanation as to why this pattern emerges. It is not that individuals are not interested in living with kin. Rather, if all individuals seek to live with as many kin as possible, no-one ends up living with many kin at all."

    Many unique human traits such as high cognition, cumulative culture and hyper-cooperation have evolved due to the social organisation patterns unique to humans.

    Although hunter-gatherer societies are increasingly under pressure from external forces, they offer the closest extant examples of human lifestyles and social organisation in the past, offering important insights into human evolutionary history.

    Senior author, Dr Andrea Migliano (UCL Anthropology), said: "Sex equality suggests a scenario where unique human traits such as cooperation with unrelated individuals could have emerged in our evolutionary past".

    Source: University College London [May 15, 2015]

  • Europe: Skeletal marker of physiological stress might indicate good, rather than poor, health

    Europe: Skeletal marker of physiological stress might indicate good, rather than poor, health

    Biological anthropologist Sharon DeWitte studies ancient skeletons that can open a window onto the human history she hopes to illuminate. But as she and graduate student Samantha Yaussy show in a recently published study, some of the markers on the skeletons that scientists use to decipher the past might need to be looked at in a new light.

    Skeletal marker of physiological stress might indicate good, rather than poor, health
    Horizontal grooves in skeletal teeth (linear enamel hypoplasia) are an indication of physiological stress on an
     individual in early childhood, between six months and six years of age [Credit: Sharon DeWitte]

    DeWitte, one of the world's foremost experts on the Black Death, which killed one-third to one-half of Europe's inhabitants over just seven years in a mid-1300s pandemic, is also interested in the periods before and after the Black Death, both in times of famine and, for the medieval era, relative plenty.

    "This was a time when you had all of these other stressors existing, like multiple infectious diseases, people living in really crowded conditions, lack of hygiene," DeWitte says. "I'm interested in looking at how famine might have affected subsequent patterns of health and risks of mortality."

    In research recently published in the >American Journal of Physical Anthropology, Yaussy and DeWitte worked with skeletal remains excavated from London's St. Mary Spital cemetery, which was in use from about 1120 to 1540 A.D. The cemetery was organized well enough over those years that modern-day researchers can assign burial groupings according to location to a number of shorter time periods within that larger 420-year time frame. Because they were focused on the effects of famine, the scientists specifically excluded burials from the Black Death era in the study.

    The way that people were buried in plots also provided important data. Large group burials within a single grave were taken to be the result of catastrophic famine losses over short periods of time, whereas single interments were categorized as "attritional" deaths, that is, deaths in "normal" times.

    Using a total of more than 1,500 individual adult remains that were almost evenly divided between famine deaths and normal deaths, DeWitte and Yaussy carefully examined the skeletons for markers that are indicative of stress during the individual's lifetime.

    One stress marker they looked for is called "linear enamel hypoplasia" (LEH), which is a horizontal groove on a tooth that results from childhood physiological stress or trauma sometime between 6 months and 6 years of age, when the tooth is forming in the jaw.

    "It could be the result of an infection, lack of nutrition, or even breaking a leg," says Yaussy. "Your enamel just stops creating itself for a day or a little longer. It starts back up again, but during that time when it was shut off, there's no enamel on that portion of the teeth, and it leaves a groove."

    They found that that stress marker, LEH, was significantly correlated with famine. "It was a pretty sensitive indicator of famine burials," Yaussy says. "Having that early life insult seems to instigate this pattern of lifelong frailty, so when a famine event occurs, it causes mortality in those individuals."

    Another indicator of life stress, though, turned out to be a horse of a different color. Using shin bones (tibia), the researchers looked for what's called periosteal lesions. It's a place on the bone where new growth on the surface has occurred in response to physical or physiological stress.

    "When it's put under stress, and it can be from something like an infection, or a break, or even just stress from carrying heavy buckets all day, bone can grow onto itself and strengthen itself," Yaussy says. "These are nonspecific -- we're not necessarily saying that it was an infection that caused it, or that it was from someone hitting their shin repeatedly. I just see that there was bone growth there, so there's some stressor that's causing the bone to generate more bone."

    In contrast to people with the LEH indicator, individuals with areas of bone regrowth were correlated with periods of normal, or attritional, death. That result came as a something of a surprise to colleagues in the field.

    "This project was a bit of a shock to some of the people at the paleopathology meetings where we presented it," Yaussy says. "A lot of people have been thinking that things like periosteal lesions are bad, that people who had them weren't especially healthy. But this study in part might be saying that those people were actually pretty healthy. It takes time, a couple of weeks, to build up this bone, so it could be that if there was some stress event that was substantial enough to kill a person before they could even register a response, we wouldn't be seeing it on the bone now."

    The unexpected result helps inform DeWitte in the larger goal of looking at what happens to populations after crises, such as the Black Death or famines, pass, and particularly how cultural norms might influence the outcomes.

    "What I'm interested in going forward is looking at access to resources before the Black Death, during normal conditions during famine conditions, and then after the Black Death, again during normal and famine conditions," Dewitte says. "Seeing if there were social factors that affected people's access to resources when there was little available and then when they became abundant again."

    "I think this might have implications for living populations, understanding how social, economic and political factors affect access to resources beyond the actual amount of resources that are available."

    Author: Steven Powell | Source: University of South Carolina [May 02, 2016]

  • UK: 750-year-old skeletons will give picture of medieval Aberdeen

    UK: 750-year-old skeletons will give picture of medieval Aberdeen

    How an Aberdonian would have looked around 750 years ago is to be reconstructed by one of the world’s top forensic anthropologists.

    750-year-old skeletons will give picture of medieval Aberdeen
    Prof Sue Black will work with skeletons discovered by archaeologists 
    [Credit: Hemedia]

    Professor Sue Black, director of the Centre for Anatomy and Human Identification at Dundee University, is in talks with city chiefs on the project after a mass haul of medieval skeletons was made in the city centre earlier this year.

    Professor Black described it as a “fascinating project” and is due to create a 3D map to give an impression of how the city forebearers may have looked.

    If the condition of the remains found underneath Aberdeen Art Gallery is good enough, a whole family could be reconstructed.

    A bronze cast of the impressions could become the centrepiece to Aberdeen’s new art gallery complex, due to open in 2017.

    Aberdeen City Council Leader, Councillor Jenny Laing, said the prospect of working with Professor Black elevated the gallery project to a new level.

    She said: “Sue Black is the world’s leading forensic anthropologist and to have her engaged in this project elevates our work to a new level and opens the door to new possibilities.”

    “These people pre-date Robert the Bruce and were alive when Henry III was on the English throne – it is fascinating to think that we could get a glimpse into their world and to consider how Aberdeen has changed through the centuries. The analysis that is being done will provide a unique insight into the people that have lived right here in Aberdeen centuries ago.

    “It is all the more special to think that they are our forefathers.”

    In March, 92 skeletons believed to date back to the 13th Century were unearthed from under Aberdeen Art Gallery during the £30 million redevelopment works.

    It is likely that the discovery of the skeletons was linked to Blackfriars, a church and friary dating to around 1230 that was destroyed during the Reformation. Archaeologists found a collection of bones of at least 40 people in three coffins and a further 52 skeletons were found in individual coffins in their own graves.

    Artefacts and treasures such as coins, coffin fixtures and textile ceramics were also found and are currently being analysed in London along with the skeletons.

    Details on disease, war or famine in that time period are now being searched for.

    Author: Alison Campsie | Source: The Scotsman [May 25, 2016]

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