The Great London [Search results for health

  • Environment: Kew report urges global scientific community to secure health of the planet

    Environment: Kew report urges global scientific community to secure health of the planet

    The first annual State of the World's Plants report, which involved more than 80 scientists and took a year to produce, is a baseline assessment of current knowledge on the diversity of plants on earth, the global threats these plants currently face, as well as the policies in place and their effectiveness in dealing with threats.

    Kew report urges global scientific community to secure health of the planet
    A fifth of the world's plant species are at risk of extinction, according to a survey by 
    Britain's Royal Botanic Gardens at Kew [Credit: AFP/Daniel Leal-Olivas]

    "This is the first ever global assessment on the state of the world's plants. We already have a 'State of the World's ...birds, sea-turtles, forests, cities, mothers, fathers, children even antibiotics' but not plants. I find this remarkable given the importance of plants to all of our lives- from food, medicines, clothing, building materials and biofuels, to climate regulation. This report therefore provides the first step in filling this critical knowledge gap." said Professor Kathy Willis, Director of Science at the Royal Botanic Gardens, Kew at the report launch on Monday.

    "But to have effect, the findings must serve to galvanise the international scientific, conservation, business and governmental communities to work together to fill the knowledge gaps we've highlighted and expand international collaboration, partnerships and frameworks for plant conservation and use," she added.

    The status of plants outlined in the report is based on the most up to date knowledge from around the world as of 2016 and is divided into three sections; describing the world's plants, global threats to plants and policies and international trade.

    Naming and Counting

    The first section focuses on the diversity of plants on earth, noting that there are now an estimated 391,000 vascular plants known to science of which 369,000 are flowering plants -- with around 2,000 new vascular plant species described annually. Some of the most exciting were found during fieldwork while many others were detected only after they have already been preserved and filed as herbarium specimens and a few have been discovered in the glasshouses at Kew.

    Kew report urges global scientific community to secure health of the planet
    Logging at the Amazon and other rainforests represents 21.3 percent of the total risk to plant species, 
    according to a study by Britain's Royal Botanic Gardens [Credit: AFP/Raphael Alves]

    One of the largest carnivorous plants known (1.5m in height), a new insect-eating plant of the sundew genus called Drosera magnifica was even first discovered on Facebook. Eighteen new species of the genus Ipomoea in the morning glory family, were described from Bolivia last year, among them a close relative of the sweet potato, Ipomoea batatas, offering exciting options for the future of this crop.

    "But there are still large parts of the world where very little is known about plants. Identification of these important plant areas is now critical." said Steve Bachman, strategic output leader for the State of the World´s Plants report, RBG Kew. "Similarly, we still only know a fraction of the genetic diversity of plants and whole-genome sequences are currently available for just 139 species of vascular plants. Activity in this area needs to speed up," he added.

    Useful plants

    In terms of the uses of plants, the report collates data from multiple data sources to reveal that at least 31,000 plant species have a documented use for medicines, food, materials and so on. The majority (17,810 plants) of those now documented have a medicinal use.

    Kew report urges global scientific community to secure health of the planet
    British scientists warn that farming -- such as mangroves being transformed into shrimp farms -- 
    poses the biggest extinction threat to plant species [Credit: AFP/Sebastien Blanc]

    Aside from the plants that are currently in use, the report looks at where collection efforts should focus to include plants that will be useful in the future. One set of plant species of critical importance to global food security are the wild relatives of crops, a pool of genetic variation that can help to drive the improvement of our crops into the future. A recent inventory has revealed that there are currently 3,546 prioritised global plant taxa identified as 'crop wild relatives' and Kew's Millennium Seed Bank (MSB) includes 688 crop wild relatives among its over 78,000 accessions, but there are still substantial gaps.

    Research in this sector has found that the traits that have been bred into crops over years of domestication are not necessarily the same ones that will provide the greatest climate resilience. Given that many of the wild populations of these species are under considerable threat due to land-use and climate change there is an urgent need to conserve those species not adequately represented in current collections. More seed banking will help preserve a wider range of alternatives to the crops on which the world over relies today (report pages 20-23).

    Climate change

    The report also explores current knowledge around the impact of climate change on plants and finds that while there is a good understanding for some regions of the world, there are still large areas for which little or no research exists. In those areas where good data is available, clear impacts are visible, including changes in flowering times, turnover in plant communities and movement of species with changing climates.

    Kew report urges global scientific community to secure health of the planet
    Tim Utteridge of Kew Gardens shows a preserved Ferocactus fordii
    [Credit: AFP/Daniel Leal-Olivas]

    Research referenced in the report shows that all but one of the world's biomes have experienced more than 10% change in land-cover type in the past decade due to the combined impacts of land-use and climate change.

    This research, led by teams at the International Center for Tropical Agriculture in Colombia is also the first of its kind to allocate timeframes for the changes in policy and practice needed to maintain food production and security in Africa. It identifies that up to 30% of areas growing maize and bananas, and up to 60% of those growing beans, are likely to become unviable by the end of the century. But it also highlights some crops like cassava and yams that are showing much greater resilience and could worth focusing on in years to come (report pages 36-39).

    "Having proof that root crops like cassava and yams are among the climate-smart crops of the future for sub Saharan Africa is vital for informing policy and planning today," added Professor Willis.

    Further research into building a climate resilient coffee economy in Ethiopia published in this report highlights how coffee production is likely to be drastically affected by climate change, but claims that this could be offset if there were interventions now to develop new areas for coffee plantations, which may even lead to gains in coffee production.

    Kew report urges global scientific community to secure health of the planet
    Kew Gardens in southwest London has one of the world's largest plant collections 
    [Credit: AFP/Daniel Leal-Olivas]

    Important plant areas

    1,771 important plant areas have been identified globally but very few currently have conservation protection. In the UK alone, 165 such sites have been recognised, including parts of the Atlantic woodlands and the Celtic rainforests which are considered to be globally important. These sites include the Lizard in Cornwall, the Brecklands in East Anglia and parts of the west coast of Scotland. Important plant areas have also been identified in several of the UK Overseas Territories including the Falkland Islands and plans are underway to extend this programme to the Caribbean UK Overseas Territories.

    Invasive species

    A large movement of invasive alien plant species is also occurring. Nearly 5000 plant species are now documented as invasive in global surveys. These plants are causing large declines in native plants, damaging natural ecosystems, transforming land-cover and often causing huge economic losses. In the UK, this includes the highly invasive Japanese knotweed (Reynoutria japonica), introduced as an ornamental plant to Britain in the mid-19th century and costing Great Britain more than £165 million annually to control (report pages 48-51).

    The report calls for closer collaboration between institutions and organisations working with invasive species to enable the establishment of a single global list that documents taxonomy, threat, distribution, control and other relevant information. Stricter enforcement of legislation and increased implementation of quarantine procedures would minimise the risk of further.

    Kew report urges global scientific community to secure health of the planet
    A technician picks up a sample of frozen DNA from a Ficus hispida at Kew Gardens 
    [Credit: AFP/Daniel Leal-Olivas]

    Plant diseases

    There are many emerging threats also occurring with plant diseases, and research effort into these diseases is skewed towards countries with a wealthier research infrastructure.

    Threats and extinction

    Best estimates lead us to believe that 21% of the world's plants are currently threatened with extinction and ongoing monitoring will allow us to determine whether the trend is of plants slipping closer towards extinction or becoming less threatened.

    Plants and policies

    Although trade in plants supports livelihoods worldwide, illegal or unsustainable trade is causing additional pressure on wild biodiversity and strict enforcement of international legislation is crucial. Adoption and implementation of policies such as CITES (Convention on International Trade in Endangered Species) have had demonstrable benefits and there is cause for optimism that the Nagoya Protocol will enhance the effectiveness with which countries conserve and utilise their biodiversity.

    One of the main plant groups that are still widely traded are orchids, a fact confirmed by data from the UK borderforce. Of all plants plants seized at Heathrow airport in 2015 over 42% were wild orchids.

    "This is the most significant horizon-scanning document to be released by Kew in recent decades and I hope as many people as possible will access the findings," said Richard Deverell, Director of the Royal Botanic Gardens, Kew.

    "Plants represent one of the most important constituents of biodiversity, the foundation of most of the world's ecosystems and hold the potential to tackle many of the world's present and future challenges. We are uniquely placed to unlock their importance and are proud to have both the catalogue of over 250 years of collections and active scientific field work globally that allows us to interpret the data so it will have multiple uses for generations to come," he added.

    Read the report >here.

    Source: Royal Botanic Gardens Kew [May 11, 2016]

  • Natural Heritage: More infectious diseases emerging because of climate change

    Natural Heritage: More infectious diseases emerging because of climate change

    The appearance of infectious diseases in new places and new hosts, such as West Nile virus and Ebola, is a predictable result of climate change, says a noted zoologist affiliated with the Harold W. Manter Laboratory of Parasitology at the University of Nebraska-Lincoln.

    More infectious diseases emerging because of climate change
    In some areas of Costa Rica, howler monkeys like this one are infected with parasites 
    once limited to capuchin and spider monkeys. After humans hunted capuchins and 
    spider monkeys out of existence in the region, the parasites immediately switched to
    howler monkeys, where they persist today [Credit: Daniel Brooks Photography]

    In an article published online today in conjunction with a special issue of the Philosophical Transactions of the Royal Society B, Daniel Brooks warns that humans can expect more such illnesses to emerge in the future, as climate change shifts habitats and brings wildlife, crops, livestock, and humans into contact with pathogens to which they are susceptible but to which they have never been exposed before.

    "It's not that there's going to be one 'Andromeda Strain' that will wipe everybody out on the planet," Brooks said, referring to the 1971 science fiction film about a deadly pathogen. "There are going to be a lot of localized outbreaks putting pressure on medical and veterinary health systems. It will be the death of a thousand cuts."

    Brooks and his co-author, Eric Hoberg, a zoologist with the U.S. National Parasite Collection of the USDA's Agricultural Research Service, have personally observed how climate change has affected very different ecosystems. During his career, Brooks has focused primarily on parasites in the tropics, while Hoberg has worked primarily in Arctic regions.

    Each has observed the arrival of species that hadn't previously lived in that area and the departure of others, Brooks said.

    "Over the last 30 years, the places we've been working have been heavily impacted by climate change," Brooks said in an interview last week. "Even though I was in the tropics and he was in the Arctic, we could see something was happening." Changes in habitat mean animals are exposed to new parasites and pathogens.

    For example, Brooks said, after humans hunted capuchin and spider monkeys out of existence in some regions of Costa Rica, their parasites immediately switched to howler monkeys, where they persist today. Some lungworms in recent years have moved northward and shifted hosts from caribou to muskoxen in the Canadian Arctic.

    But for more than 100 years, scientists have assumed parasites don't quickly jump from one species to another because of the way parasites and hosts co-evolve.

    Brooks calls it the "parasite paradox." Over time, hosts and pathogens become more tightly adapted to one another. According to previous theories, this should make emerging diseases rare, because they have to wait for the right random mutation to occur.

    However, such jumps happen more quickly than anticipated. Even pathogens that are highly adapted to one host are able to shift to new ones under the right circumstances.

    Brooks and Hoberg call for a "fundamental conceptual shift" recognizing that pathogens retain ancestral genetic capabilities allowing them to acquire new hosts quickly.

    "Even though a parasite might have a very specialized relationship with one particular host in one particular place, there are other hosts that may be as susceptible," Brooks said.

    In fact, the new hosts are more susceptible to infection and get sicker from it, Brooks said, because they haven't yet developed resistance.

    Though resistance can evolve fairly rapidly, this only changes the emergent pathogen from an acute to a chronic disease problem, Brooks adds.

    "West Nile Virus is a good example - no longer an acute problem for humans or wildlife in North America, it nonetheless is hhere to stay," he said.

    The answer, Brooks said, is for greater collaboration between the public and veterinary health communities and the "museum" community - the biologists who study and classify life forms and how they evolve.

    In addition to treating human cases of an emerging disease and developing a vaccine for it, he said, scientists need to learn which non-human species carry the pathogen.

    Knowing the geographic distribution and the behavior of the non-human reservoirs of the pathogen could lead to public health strategies based on reducing risk of infection by minimizing human contact with infected animals, much likethose that reduced the incidence of malaria and yellow fever by reducing human contact with mosquitos.

    Museum scientists versed in understanding the evolutionary relationships among species could use this knowledge to anticipate the risk of the pathogen becoming established outside of its native range.

    Brooks, who earned his bachelor's and master's degrees from the University of Nebraska-Lincoln, was a zoology professor at the University of Toronto for 30 years until he retired early in 2011 to devote more time to his study of emerging infectious disease. In addition to being a senior research fellow with UNL's Manter Laboratory, he is a visiting senior fellow at the Universidade Federal do Parana, Brazil, funded by the Ciencias sem Fronteiras (Sciences without Borders) of the Brazilian government, and a visiting scholar with Debrecen University in Hungary.

    Brooks' and Hoberg's article, "Evolution in action: climate change, biodiversity dynamics and emerging infectious disease," is part of a Philosophical Transactions of the Royal Society B issue on "Climate change and vector-borne diseases of humans," edited by Paul Parham, a specialist in infectious disease epidemiology at Imperial College in London.

    "We have to admit we're not winning the war against emerging diseases," Brooks said. "We're not anticipating them. We're not paying attention to their basic biology, where they might come from and the potential for new pathogens to be introduced."

    Source: University of Nebraska-Lincoln [February 16, 2015]

  • Europe: Skeletal marker of physiological stress might indicate good, rather than poor, health

    Europe: Skeletal marker of physiological stress might indicate good, rather than poor, health

    Biological anthropologist Sharon DeWitte studies ancient skeletons that can open a window onto the human history she hopes to illuminate. But as she and graduate student Samantha Yaussy show in a recently published study, some of the markers on the skeletons that scientists use to decipher the past might need to be looked at in a new light.

    Skeletal marker of physiological stress might indicate good, rather than poor, health
    Horizontal grooves in skeletal teeth (linear enamel hypoplasia) are an indication of physiological stress on an
     individual in early childhood, between six months and six years of age [Credit: Sharon DeWitte]

    DeWitte, one of the world's foremost experts on the Black Death, which killed one-third to one-half of Europe's inhabitants over just seven years in a mid-1300s pandemic, is also interested in the periods before and after the Black Death, both in times of famine and, for the medieval era, relative plenty.

    "This was a time when you had all of these other stressors existing, like multiple infectious diseases, people living in really crowded conditions, lack of hygiene," DeWitte says. "I'm interested in looking at how famine might have affected subsequent patterns of health and risks of mortality."

    In research recently published in the >American Journal of Physical Anthropology, Yaussy and DeWitte worked with skeletal remains excavated from London's St. Mary Spital cemetery, which was in use from about 1120 to 1540 A.D. The cemetery was organized well enough over those years that modern-day researchers can assign burial groupings according to location to a number of shorter time periods within that larger 420-year time frame. Because they were focused on the effects of famine, the scientists specifically excluded burials from the Black Death era in the study.

    The way that people were buried in plots also provided important data. Large group burials within a single grave were taken to be the result of catastrophic famine losses over short periods of time, whereas single interments were categorized as "attritional" deaths, that is, deaths in "normal" times.

    Using a total of more than 1,500 individual adult remains that were almost evenly divided between famine deaths and normal deaths, DeWitte and Yaussy carefully examined the skeletons for markers that are indicative of stress during the individual's lifetime.

    One stress marker they looked for is called "linear enamel hypoplasia" (LEH), which is a horizontal groove on a tooth that results from childhood physiological stress or trauma sometime between 6 months and 6 years of age, when the tooth is forming in the jaw.

    "It could be the result of an infection, lack of nutrition, or even breaking a leg," says Yaussy. "Your enamel just stops creating itself for a day or a little longer. It starts back up again, but during that time when it was shut off, there's no enamel on that portion of the teeth, and it leaves a groove."

    They found that that stress marker, LEH, was significantly correlated with famine. "It was a pretty sensitive indicator of famine burials," Yaussy says. "Having that early life insult seems to instigate this pattern of lifelong frailty, so when a famine event occurs, it causes mortality in those individuals."

    Another indicator of life stress, though, turned out to be a horse of a different color. Using shin bones (tibia), the researchers looked for what's called periosteal lesions. It's a place on the bone where new growth on the surface has occurred in response to physical or physiological stress.

    "When it's put under stress, and it can be from something like an infection, or a break, or even just stress from carrying heavy buckets all day, bone can grow onto itself and strengthen itself," Yaussy says. "These are nonspecific -- we're not necessarily saying that it was an infection that caused it, or that it was from someone hitting their shin repeatedly. I just see that there was bone growth there, so there's some stressor that's causing the bone to generate more bone."

    In contrast to people with the LEH indicator, individuals with areas of bone regrowth were correlated with periods of normal, or attritional, death. That result came as a something of a surprise to colleagues in the field.

    "This project was a bit of a shock to some of the people at the paleopathology meetings where we presented it," Yaussy says. "A lot of people have been thinking that things like periosteal lesions are bad, that people who had them weren't especially healthy. But this study in part might be saying that those people were actually pretty healthy. It takes time, a couple of weeks, to build up this bone, so it could be that if there was some stress event that was substantial enough to kill a person before they could even register a response, we wouldn't be seeing it on the bone now."

    The unexpected result helps inform DeWitte in the larger goal of looking at what happens to populations after crises, such as the Black Death or famines, pass, and particularly how cultural norms might influence the outcomes.

    "What I'm interested in going forward is looking at access to resources before the Black Death, during normal conditions during famine conditions, and then after the Black Death, again during normal and famine conditions," Dewitte says. "Seeing if there were social factors that affected people's access to resources when there was little available and then when they became abundant again."

    "I think this might have implications for living populations, understanding how social, economic and political factors affect access to resources beyond the actual amount of resources that are available."

    Author: Steven Powell | Source: University of South Carolina [May 02, 2016]

  • UK: More than one in ten UK species threatened with extinction

    UK: More than one in ten UK species threatened with extinction

    Some of the UK's leading nature experts have delivered a clarion call for action to help save many of the nation's native wildlife species from extinction.

    More than one in ten UK species threatened with extinction
    Climate change, urban expansion and agricultural intensification blamed for risk to some 
    of Britain's best loved species [Credit Philip Braude]

    A critical new report, called >State of Nature 2016 and published, delivered the clearest picture to date of the status of our native species across land and sea. Crucially, the report attributes much of the imposing threat to changing agricultural land management, climate change and sustained urban development. These threaten many of Britain's best loved species including water voles -- the fastest declining mammal.

    The startling report reveals that more than half (56%) of UK species studied have declined since 1970, while more than one in ten (1,199 species) of the nearly 8000 species assessed in the UK are under threat of disappearing altogether.

    The report, produced by a coalition of more than 50 leading wildlife and research organisations and specialists including Dr Fiona Mathews from the University of Exeter, demands immediate action to stave off the growing threat to Britain's unique wildlife.

    Dr Mathews, an Associate Professor in Mammalian Biology at the University of Exeter and Chair of the Mammal Society, who helped write the report, said many British mammals are under pressure from house building and intensification of agriculture.

    She said: "The reality is that our human population is expanding and we need urgently to work out how we can live alongside our wildlife. For example, water voles are one of our fastest declining species, and many thousands of kilometres of their habitat are affected by development every year.

    "We are therefore researching ways to ensure their survival, supported by our water vole appeal fund. In the summer, we launched best-practice guidance on looking after water voles during development, and these are now being followed by industry, helping to ensure that "Ratty" survives on ponds, rivers and canals throughout the UK."

    As the UK Government and devolved administrations move forward in the light of the EU Referendum result, there is an opportunity to secure world leading protection for our species and restoration of our nature. Now is the time to make ambitious decisions and significant investment in nature to ensure year-on-year improvement to the health and protection of the UK's nature and environment for future generations. The Mammal Society is currently drawing up a 'Red List' of the most threated species, to help ensure that scarce funds are directed to the animals most in need.

    Dr Mathews added: "The findings emphasise that whole ecosystems, not just one or two species, are under threat.

    "We are a nation of nature-lovers -- just look at the success of "Countryfile" and "Springwatch." Every week thousands of volunteers are out recording wildlife and helping with practical habitat management. We also depend on the natural environment for a huge number of goods and services, not to mention our own health and wellbeing.

    "Yet successive governments have cut funding for the environment, and conservation concerns are all too often vilified as a barrier to urban development, infrastructure projects or efficient food production. This is a moment to reflect on what sort of country we want for our children -- a sustainable future for them depends on our decisions now."

    The State of Nature 2016 UK report will be launched by Sir David Attenborough and UK conservation and research organisations at the Royal Society in London on Wednesday, September 14, while separate events will be held in Edinburgh, Cardiff and Belfast over the next week.

    Sir David Attenborough said: "The natural world is in serious trouble and it needs our help as never before. The rallying call issued after the State of Nature report in 2013 has promoted exciting and innovative conservation projects. Landscapes are being restored, special places defended, struggling species being saved and brought back. But we need to build significantly on this progress if we are to provide a bright future for nature and for people.

    "The future of nature is under threat and we must work together -- -Governments, conservationists, businesses and individuals -- -to help it. Millions of people in the UK care very passionately about nature and the environment and I believe that we can work together to turn around the fortunes of wildlife."

    In order to reduce the impact we are having on our wildlife, and to help struggling species, we needed to understand what's causing these declines. Using evidence from the last 50 years, experts have identified that significant and ongoing changes in agricultural practices are having the single biggest impact on nature.

    The widespread decline of nature in the UK remains a serious problem to this day. For the first time scientists have uncovered how wildlife has fared in recent years. The report reveals that since 2002 more than half (53%) of UK species studied have declined and there is little evidence to suggest that the rate of loss is slowing down.

    Mark Eaton, lead author on the report, said:"Never before have we known this much about the state of UK nature and the threats it is facing. Since the 2013, the partnership and many landowners have used this knowledge to underpin some amazing scientific and conservation work. But more is needed to put nature back where it belongs -- we must continue to work to help restore our land and sea for wildlife.

    "There is a real opportunity for the UK Government and devolved administrations to build on these efforts and deliver the significant investment and ambitious action needed to bring nature back from the brink.

    "Of course, this report wouldn't have been possible without the army of dedicated volunteers who brave all conditions to survey the UK's wildlife. Knowledge is the most essential tool that a conservationist can have, and without their efforts, our knowledge would be significantly poorer."

    Derek Crawley, Atlas Office for the Mammal Society, said "New technology now enables volunteers to share information more easily than ever before. Our MammalTracker app is freely available from the App Store, or sightings of mammals can be recorded via our website. We will also be sharing information on how to make the most of volunteer programmes at a special meeting in the autumn.

    Source: University of Exeter [September 23, 2016]

  • Forensics: New research to shed fresh light on the impact of industrialisation

    Forensics: New research to shed fresh light on the impact of industrialisation

    The Museum of London today announced a ground-breaking research project to explore the effects of industrialisation on Londoners. The research hopes to uncover new clues about the very nature of disease and how it has affected people as Britain has moved into the age of industrialisation.

    New research to shed fresh light on the impact of industrialisation
    Some of London’s most important skeletons will be digitally x-rayed and scanned 
    in a new archaeological investigation linking “man-made” diseases with
     the industrialisation of the city [Credit: © Museum of London]

    The research has been made possible by a City of London Archaeological Trust grant from a bequest made by the late Rosemary Green.

    John Schofield, Secretary of the City of London Archaeological Trust, said: “The City of London Archaeological Trust is very happy that the Rosemary Green bequest is used to gather this cutting-edge data on the signs of industrialisation in the skeletal collections on the Museum of London.”

    Leading the project is Jelena Bekvalac, based at the Museum of London’s Centre for Human Bioarcheology, along with her research team, Gaynor Western and Mark Farmer.

    Jelena Bekvalac, said: “The most tangible evidence we have for the long-term consequences of the industrialisation process upon us is, quite simply, written in our bones. Using the very latest digital technology, we will examine the skeletal remains of over 1,000 adult men and women from industrial-era London in addition to a further 500 skeletons from the medieval metropolis.

    New research to shed fresh light on the impact of industrialisation
    More than 1,000 adult men and women from the industrial revolution period,
     as well as 500 more from the medieval metropolis, will be used in quest to
     find out how the era affected the population at the Museum of London’s 
    Centre for Human Bioarchaeology [Credit: © Museum of London]

    “Modern health trends have seen a shift towards increasing life expectancy but we want to look again at what are often thought of as ‘man-made’ conditions like obesity and cancer. Given today’s more sedentary lifestyles, far removed from the physically active and natural existence of most of our forebears, there are some big questions about the origins of these diseases and how they relate to the modern environment.”

    The research aims to address some of these questions by analysing diseases affecting the human skeleton. The museum will use the latest clinical techniques, including direct digital radiography, CT scanning and 3D modelling, to get a better understanding of what the bones tell us and to assess their change over time. The research aims to examine the influence of the industrial revolution, a pivotal catalyst in the formation of the modern age, on the changing nature of disease – from the medieval and post-medieval periods through to the present day.

    The project offers an exciting opportunity to digitise some of London’s most important skeletal collections, while simultaneously telling a new story about the health of Londoners over time.

    This work will culminate in the creation of an extensive new interactive digital resource that can be explored online. Jelena Bekvalac plans to make an immediate start on the digital scanning. She aims to publish her team’s findings as soon as possible and deliver a series of lectures about the work.

    Source: Museum of London [April 24, 2015]

  • Genetics: A federal origin of Stone Age farming

    Genetics: A federal origin of Stone Age farming

    The transition from hunter-gatherer to sedentary farming 10,000 years ago occurred in multiple neighbouring but genetically distinct populations according to research by an international team including UCL.

    A federal origin of Stone Age farming
    The Fertile Crescent (shaded) on a political map of the Near and South East. In blue are the the archaeological sites
     in Iran with genomes from the Neolithic period that are ancestral to modern-day South Asians. In red are Neolithic
     sites with genomes that are ancestral to all European early farmers [Credit: ©: Joachim Burger, JGU]

    “It had been widely assumed that these first farmers were from a single, genetically homogeneous population. However, we’ve found that there were deep genetic differences in these early farming populations, indicating very distinct ancestries,” said corresponding author Dr Garrett Hellenthal, UCL Genetics.

    The study, published today in >Science and funded by Wellcome and Royal Society, examined ancient DNA from some of the world’s first farmers from the Zagros region of Iran and found it to be very different from the genomes of early farmers from the Aegean and Europe. The team identified similarities between the Neolithic farmer’s DNA and that of living people from southern Asia, including from Afghanistan, Pakistan, Iran, and Iranian Zoroastrians in particular.

    “We know that farming technologies, including various domestic plants and animals, arose across the Fertile Crescent, with no particular centre” added co-author Professor Mark Thomas, UCL Genetics, Evolution & Environment.

    “But to find that this region was made up of highly genetically distinct farming populations was something of a surprise. We estimated that they separated some 46 to 77,000 years ago, so they would almost certainly have looked different, and spoken different languages. It seems like we should be talking of a federal origin of farming.”

    A federal origin of Stone Age farming
    An approximately 10,000 year old skull from the Neolithic Tepe Abdul Hossein 
    [Credit: © Fereidoun Biglari, National Museum of Iran]

    The switch from mobile hunting and gathering to sedentary farming first occurred around 10,000 years ago in south-western Asia and was one of the most important behavioural transitions since humans first evolved in Africa some 200,000 years ago. It led to profound changes in society, including greater population densities, new diseases, poorer health, social inequality, urban living, and ultimately, the rise of ancient civilizations.

    Animals and plants were first domesticated across a region stretching north from modern-day Israel, Palestine and Lebanon to Syria and eastern Turkey, then east into, northern Iraq and north-western Iran, and south into Mesopotamia; a region known as the Fertile Crescent.

    “Such was the impact of farming on our species that archaeologists have debated for more than 100 years how it originated and how it was spread into neighbouring regions such as Europe, North Africa and southern Asia,” said co-author Professor Stephen Shennan, UCL Institute of Archaeology.

    “We’ve shown for the first time that different populations in different parts of the Fertile Crescent were coming up with similar solutions to finding a successful way of life in the new conditions created by the end of the last Ice Age.”

    A federal origin of Stone Age farming
    Analysis of ancient DNA in the laboratory [Credit: ©: JGU Palaeogenetics Group]

    By looking at how ancient and living people share long sections of DNA, the team showed that early farming populations were highly genetically structured, and that some of that structure was preserved as farming, and farmers, spread into neighbouring regions; Europe to the west and southern Asia to the east.

    “Early farmers from across Europe, and to some extent modern-day Europeans, can trace their DNA to early farmers living in the Aegean, whereas people living in Afghanistan, Pakistan, Iran and India share considerably more long chunks of DNA with early farmers in Iran. This genetic legacy of early farmers persists, although of course our genetic make-up subsequently has been reshaped by many millennia of other population movements and intermixing of various groups,” concluded Dr Hellenthal.

    Source: University College London [July 14, 2016]

  • Environment: Wildfire on warming planet requires adaptive capacity at local, national, international scales

    Environment: Wildfire on warming planet requires adaptive capacity at local, national, international scales

    Industrialized nations that view wildfire as the enemy have much to learn from people in some parts of the world who have learned to live compatibly with wildfire, says a team of fire research scientists.

    Wildfire on warming planet requires adaptive capacity at local, national, international scales
    A locale in the French Western Pyrenees, where communities practice fire management to maintain seasonally flammable 
    grassland, shrub and woodland patches for forage and grazing animals [Credit: Michael Coughlan]

    The interdisciplinary team say there is much to be learned from these "fire-adaptive communities" and they are calling on policy makers to tap that knowledge, particularly in the wake of global warming.

    Such a move is critical as climate change makes some landscapes where fire isn't the norm even more prone to fire, say the scientists in a new report published in a special issue of the >Philosophical Transactions of the Royal Society B.

    "We tend to treat modern fire problems as unique, and new to our planet," said fire anthropologist Christopher Roos, Southern Methodist University, Dallas, lead author of the report. "As a result, we have missed the opportunity to recognize the successful properties of communities that have a high capacity to adapt to living in flammable landscapes—in some cases for centuries or millennia."

    One such society is the ethnically Basque communities in the French Western Pyrenees, who practice fire management to maintain seasonally flammable grassland, shrub and woodland patches for forage and grazing animals. But the practice is slowly being lost as young people leave farming.

    Additionally, Aboriginal people in the grasslands of Western Australia use fire as part of their traditional hunting practices. Children begin burning at a very young age, and the everyday practice is passed down. These fires improve hunting successes but also reduce the impact of drought on the size and ecological severity of lightning fires.

    Social institutions support individual benefits, preserve common good

    Fire-adaptive communities have social institutions in place that support individual benefits from fire-maintained landscapes while preserving the common good, said Roos, whose fire research includes long-term archaeological and ecological partnerships with the Pueblo of Jemez in New Mexico.

    "These institutions have been shaped by long-histories with wildfire, appropriate fire-use, and the development of social mechanisms to adjudicate conflicts of interest," said Roos, an associate professor in the SMU Department of Anthropology. "There is a wealth of tried and tested information that should be considered in designing local fire management."

    The authors note that globally, a large number of people use fire as a tool to sustain livelihoods in ways that have been handed down across many generations. These include indigenous Australians and North Americans, South Asian forest dwellers, European farmers, and also hunters, farmers and herders in tropical savannahs.

    Global Warming will likely bring new fire problems, more flammable landscapes

    Global Warming will likely bring new fire problems, such as making some landscapes more flammable, Roos said. More effort will be required to balance conflicting fire management practices between adjacent cultures. Currently most fire-related research tends to be undertaken by physical or biological scientists from Europe, the United States and Australia. Often the research treats fire challenges as exclusively contemporary phenomena for which history is either absent or irrelevant.

    "We need national policy that recognizes these dynamic challenges and that will support local solutions and traditional fire knowledge, while providing ways to disseminate scientific information about fire," Roos said.

    The authors point out that one of the greatest policy challenges of fire on a warming planet are the international consequences of smoke plumes and potential positive feedbacks on climate through carbon emissions. Most infamously, wildfire smoke plumes have had extraordinary health impacts during Southeast Asian "haze" events, which result in increased hospitalization and mortality in the region.

    Not all fire is a disaster; we must learn to live with and manage fire

    Carbon emissions from wildfires can be as much as 40 percent of fossil fuel emissions in any given year over the last decade. Although only deforestation fires and land conversion are a net carbon source to the atmosphere, the contribution of wildfires to global carbon emissions is non-trivial and should be a formal component of international climate dialogs.

    "It is important to emphasize that not all fire is a disaster and we must learn how to both live with as well as manage fire," said co-author Andrew Scott, earth sciences professor at Royal Holloway University of London.

    The report, "Living on a flammable planet: interdisciplinary, cross-scalar and varied cultural lessons, prospects and challenges," was published May 23, 2016 by The Royal Society, the U.K.'s independent scientific academy.

    Authors call for holistic study of fire on Earth

    The authors are from the United States, Great Britain, Canada, Australia, South Africa and Spain. The synthesis emerged from four days of international meetings sponsored by the Royal Society - the first of its kind for fire sciences.

    The authors advocate for greater collaboration among researchers studying all aspects of fire.

    Pyrogeography—the holistic study of fire on Earth, "may be one way to provide unity to the varied fire research programs across the globe," the authors write.

    "Fire researchers across disciplines from engineering, the natural sciences, social sciences and the humanities need to develop a common language to create a holistic wildfire science," said Roos. "The magnitude of the wildfire challenges we face on a warming planet will demand greater collaboration and integration across disciplines, but our job won't be done unless we are also able to translate our research for policymakers, land managers, and the general public."

    Source: Southern Methodist University [June 01, 2016]

  • Genetics: First fine-scale genetic map of the British Isles

    Genetics: First fine-scale genetic map of the British Isles

    Many people in the UK feel a strong sense of regional identity, and it now appears that there may be a scientific basis to this feeling, according to a landmark new study into the genetic makeup of the British Isles.

    First fine-scale genetic map of the British Isles
    Subtle differences in the genes of more than 2,000 people in England, Scotland, Wales 
    and Northern Ireland reveal 17 distinct groups, represented by different symbols 
    and colors on the map [Credit: Stephen Leslie; Contains OS data 
    © Crown copyright and database right 2012; © EuroGeographics
     for some administrative boundaries]

    An international team, led by researchers from the University of Oxford, UCL (University College London) and the Murdoch Childrens Research Institute in Australia, used DNA samples collected from more than 2,000 people to create the first fine-scale genetic map of any country in the world.

    Their findings, published in Nature, show that prior to the mass migrations of the 20th century there was a striking pattern of rich but subtle genetic variation across the UK, with distinct groups of genetically similar individuals clustered together geographically.

    By comparing this information with DNA samples from over 6,000 Europeans, the team was also able to identify clear traces of the population movements into the UK over the past 10,000 years. Their work confirmed, and in many cases shed further light on, known historical migration patterns.

    Key findings

    • There was not a single "Celtic" genetic group. In fact the Celtic parts of the UK (Scotland, Northern Ireland, Wales and Cornwall) are among the most different from each other genetically. For example, the Cornish are much more similar genetically to other English groups than they are to the Welsh or the Scots.
    • There are separate genetic groups in Cornwall and Devon, with a division almost exactly along the modern county boundary.
    • The majority of eastern, central and southern England is made up of a single, relatively homogeneous, genetic group with a significant DNA contribution from Anglo-Saxon migrations (10-40% of total ancestry). This settles a historical controversy in showing that the Anglo-Saxons intermarried with, rather than replaced, the existing populations.
    • The population in Orkney emerged as the most genetically distinct, with 25% of DNA coming from Norwegian ancestors. This shows clearly that the Norse Viking invasion (9th century) did not simply replace the indigenous Orkney population.
    • The Welsh appear more similar to the earliest settlers of Britain after the last ice age than do other people in the UK.
    • There is no obvious genetic signature of the Danish Vikings, who controlled large parts of England ("The Danelaw") from the 9th century.
    • There is genetic evidence of the effect of the Landsker line -- the boundary between English-speaking people in south-west Pembrokeshire (sometimes known as "Little England beyond Wales") and the Welsh speakers in the rest of Wales, which persisted for almost a millennium.
    • The analyses suggest there was a substantial migration across the channel after the original post-ice-age settlers, but before Roman times. DNA from these migrants spread across England, Scotland, and Northern Ireland, but had little impact in Wales.
    • Many of the genetic clusters show similar locations to the tribal groupings and kingdoms around end of the 6th century, after the settlement of the Anglo-Saxons, suggesting these tribes and kingdoms may have maintained a regional identity for many centuries.

    The Wellcome Trust-funded People of the British Isles study analysed the DNA of 2,039 people from rural areas of the UK, whose four grandparents were all born within 80km of each other. Because a quarter of our genome comes from each of our grandparents, the researchers were effectively sampling DNA from these ancestors, allowing a snapshot of UK genetics in the late 19th Century. They also analysed data from 6,209 individuals from 10 (modern) European countries.

    To uncover the extremely subtle genetic differences among these individuals the researchers used cutting-edge statistical techniques, developed by four of the team members. They applied these methods, called fineSTRUCTURE and GLOBETROTTER, to analyse DNA differences at over 500,000 positions within the genome. They then separated the samples into genetically similar individuals, without knowing where in the UK the samples came from. By plotting each person onto a map of the British Isles, using the centre point of their grandparents' birth places, they were able to see how this distribution correlated with their genetic groupings.

    The researchers were then able to "zoom in" to examine the genetic patterns in the UK at levels of increasing resolution. At the broadest scale, the population in Orkney (islands to the north of Scotland) emerged as the most genetically distinct. At the next level, Wales forms a distinct genetic group, followed by a further division between north and south Wales. Then the north of England, Scotland, and Northern Ireland collectively separate from southern England, before Cornwall forms a separate cluster. Scotland and Northern Ireland then separate from northern England. The study eventually focused at the level where the UK was divided into 17 genetically distinct clusters of people.

    Dr Michael Dunn, Head of Genetics & Molecular Sciences at the Wellcome Trust, said: "These researchers have been able to use modern genetic techniques to provide answers to the centuries' old question -- where we come from. Beyond the fascinating insights into our history, this information could prove very useful from a health perspective, as building a picture of population genetics at this scale may in future help us to design better genetic studies to investigate disease."

    Source: Wellcome Trust [March 18, 2015]

  • Natural Heritage: Scientists warn only 'simplified', degraded tropical forest may remain by end of century

    Natural Heritage: Scientists warn only 'simplified', degraded tropical forest may remain by end of century

    A new and more dangerous phase of impacts on the world's remaining tropical forests is emerging, threatening to simplify the world's most diverse ecosystem including mass species loss, according to new UCL-led research published today in Science.

    Scientists warn only 'simplified', degraded tropical forest may remain by end of century
    Deforestation in Tesso Nilo, Sumatra [Credit: WWF]

    The impact of humans on these areas has been increasing for millennia and today more than three-quarters of the world's remaining tropical forests have been degraded by human actions.

    The scientists identified three prior phases of expanding impacts, the first when hunter-gatherers moved into tropical forests and the second following the emergence of tropical agriculture, some 6,000 years ago. Under both, the overall health of tropical forests was maintained.

    Today, we live in the third phase, marked by much greater impacts, with distant decision-makers directing how land is used, including permanent intensive agriculture, often for soybeans or palm oil, frontier industrial logging for timber export, cross-continental species invasions, and early climate change impacts. The scientists term this phase the era of 'Global Integration', affecting even the most remote areas.

    Lead author, tropical forest expert Dr Simon Lewis (UCL Geography and University of Leeds) said: "Earth has lost 100 million hectares of tropical forest over the last 30 years, mostly to agricultural developments. Few people think about how intertwined with tropical forests we all are. Many foodstuffs include palm oil which comes from once pristine Asian tropical forest, while remaining intact forests are buffering the rate of climate change by absorbing about a billion tonnes of carbon each year."

    Current trends look set to intensify without major policy changes, as global food demand is projected to double, over 25 million kilometres of road are predicted to be built by 2050, and climate change intensifies, ushering in a new phase of human dominance of tropical forests.

    Dr Lewis added: "I fear a global simplification of the world's most complex forests. Deforestation, logging and road building all create fragmented patches of forest. However, as the climate rapidly changes the plants and animals living in the rainforest will need to move to continue to live within their ecological tolerances. How will they move? This is a recipe for the mass extinction of tropical forest species this century.

    "What is needed are unbroken areas of forest that link today's core tropical regions with forest areas about 4 degrees cooler, so as temperatures rise and rainfall patterns change species have a better chance of surviving rapid 21st century climate change. We need to bring conservation in line with the reality of climate change."

    The authors note that while deforestation and degradation continue, more optimistically, logged forest retains many environmental benefits, and marginal agricultural lands are being abandoned, which can return back to forest.

    Dr David Edwards (University of Sheffield), co-author of the study, said: "Much biodiversity still remains in selectively logged forests, and can recover in secondary forests that grow on abandoned farmland. There is abundant potential to incorporate these forests into global plans to make tropical biodiversity climate change ready.

    "Despite their value for biodiversity, logged-over and old secondary forests are frequently threatened by conversion to species-poor agricultural plantations. We urgently need to protect these human-impacted forests, especially in regions such as Southeast Asia where almost nowhere is left undegraded."

    A suite of policy measures can help tropical forests survive, including giving forest dwellers formal collective legal rights over their land, which previous studies have shown is one of the best ways of preserving forests. A study of 292 protected areas in Amazonia showed that indigenous reserves were the most effective at avoiding deforestation in high pressure areas.

    Most of the financial benefits of logging and plantation agriculture, such as palm oil, flow out of the forests. Ensuring local people have collective long-term rights over their lands would mean that benefits flowing from forest lands accrue to local people. This can provide the beginnings of programs of 'development without destruction', tackling poverty while maintaining forests. This, the authors argue, provides human rights and conservation win-wins.

    Dr Lewis added: "With long-term certainty of tenure people can plan, maintaining forests while investing in improving agricultural productivity without expanding into forested lands. Forest dwellers won't be perfect managers of forests, but they won't look for a quick profit and then move on, as big businesses often do.

    "This is a pivotal year for the global environment. There are some good signs for the world's tropical forests, with the UN New York Declaration on Forests agreeing to not only halt deforestation, but also restore 150 million hectares of forest. However, there are ominous signs too, with the palm oil industry having driven the world's highest deforestation rates in South East Asia now gearing up to repeat this process across Africa.

    "The Paris climate change talks in December are doubly important for forests and forest communities. The levels of emission cuts will be a critical factor in determining how many tropical forest plants and animals go extinct over the coming decades and centuries. The agreements on reducing deforestation, including durable finance, will be pivotal. The final test will be whether some funds for adaptation will include land-use planning to retain forest connectivity as the climate rapidly changes."

    Source: University College London [August 24, 2015]

  • Scotland: 'Skeletons: Our Buried Bones' at the Hunterian Museum, Glasgow

    Scotland: 'Skeletons: Our Buried Bones' at the Hunterian Museum, Glasgow

    This special exhibition unearths the stories behind four skeletons from the Museum of London’s 20,000-strong collection and four from burial grounds across Scotland. This is a touring exhibition that, after Glasgow, will travel to Bristol and Leeds in 2017, displaying the Museum of London’s skeletons alongside bones discovered locally. In-depth analysis by experts at the Museum of London has provided insights into the health and history of each individual, helping to bring to life the stories that have long been hidden beneath the ground.

    'Skeletons: Our Buried Bones' at the Hunterian Museum, Glasgow

    The skeletons on display in Glasgow reflect a rich and varied past, with individuals coming from diverse locations, both geographically and socially, and periods of time. Excavations have uncovered burial grounds across the UK, ranging from the Neolithic period through the Iron Age to Roman London and up to the 19th century. Each individual skeleton reveals aspects of their life and times, including fractures and trauma, multiple myeloma – cancer, the effects of syphilis, rickets or arthritis, and tooth decay.

    Emily Sargent, curator at Wellcome Collection, said: “Spanning thousands of years and from opposite ends of the country and social scales, the bones of these individuals offer us a rare and special glimpse into history. Yet we identify with their rotten teeth or broken bones, and are reminded that skeletons can tell us more about what people lived with, rather than what they died from.”

    Sharon Ament, Director of the Museum of London, said: “This is the first time our skeletons have gone on tour and really shows how museums at opposite ends of the UK can work together to show their joint collections. We can learn a lot from the bones of our ancestors, who all lived through very different versions of the London we know today, and this is a wonderful opportunity to share their stories alongside those of their local Scottish counterparts for the first time.”


    Research carried out on the skeletons has helped shed new light on the grounds they were discovered in and the circumstances in which they were buried, from plague pits in urban London to the beaches of South Uist. Specially commissioned photographs by photographer Thomas Adank capture the sites as they are now, and will be displayed in the exhibition next to each skeleton, contextualising them as a reminder of the layers of human history all around us.

    Jelena Bekvalac, Curator of Human Osteology at the Museum of London, said: “Research carried out on these skeletons has given us vital clues into the lives of these individuals, some of whom lived thousands of years ago. Putting them in context with where they were buried and what those sites look like now will mean visitors will have a real, tangible connection to these people. It is a unique opportunity for the skeletons from London to be displayed in Glasgow alongside their Scottish counterparts, and truly demonstrates the rich diversity of burial in the British Isles.”

    Professor David Gaimster, Director of The Hunterian, added: “We are delighted to be working in partnership with Wellcome Collection and the Museum of London on this fascinating exhibition. ‘Skeletons: Our Buried Bones’ offers a unique insight into the way people lived, worked and died.”

    ‘Skeletons: Our Buried Bones’ is a collaboration between Wellcome Collection and Museum of London, touring to Glasgow, Bristol and Leeds over 2016-2018. It’s based on ‘Skeletons: London’s Buried Bones’, originally shown at Wellcome Collection in 2008 and is curated by Emily Sargent and Jelena Bekvalac. 

    Source: The Hunterian Museum [August 18, 2016]

  • Exhibitions: Egyptian mummies virtually unwrapped in Australia

    Exhibitions: Egyptian mummies virtually unwrapped in Australia

    The hidden secrets of Egyptian mummies up to 3,000 years old have been virtually unwrapped and reconstructed for the first time using cutting-edge scanning technology in a joint British-Australian exhibition.

    Egyptian mummies virtually unwrapped in Australia
    A young visitor looks at a 3D image of a CT scan of an Egyptian mummy, during a preview for a joint 
    British-Australian exhibition in Sydney [Credit: AFP/William West]

    Three-dimensional images of six mummies aged between 900BC and 140-180AD from ancient Egypt, which have been held at the British Museum but never physically unwrapped, give an insight into what it was like to live along the Nile river thousands of years ago.

    "We are revealing details of all their physical remains as well as the embalming material used by the embalmers like never before," the British Museum's physical anthropology curator Daniel Antoine told AFP at the Powerhouse Museum in Sydney Thursday. "What we are showing to the public is brand-new discoveries of their insides."

    Two of the travelling mummies were previously exhibited at the British Museum in 2014, with the other four being revealed to the world for the first time in the Sydney show that opens on Saturday.

    Egyptian mummies virtually unwrapped in Australia
    A young visitor looks at a 3D image of a CT scan of an Egyptian mummy, during a preview for a joint 
    British-Australian exhibition in Sydney [Credit: AFP/William West]

    A dual-energy computed tomography (CT) scanner at the Royal Brompton Hospital in London—of which only a handful are in operation around the world—was used to obtain thousands of slices of images of the mummies, with volumetric software then harnessed to create 3D models, Antoine said.

    It effectively allows visitors to virtually peel back the layers of history through interactive 3D visualisations of the CT scans.

    "I've been able to image the arteries of the mummies, the ones that have been left, and I'm able to look at whether they are suffering from diseases which many people are suffering from today, (such as) cardiovascular diseases," Antoine added.

    Egyptian mummies virtually unwrapped in Australia
    A 3D image of a CT scan of an Egyptian mummy is projected next to its sarcophagus 
    [Credit: AFP/William West]

    He believes the mummies can be rescanned in a decade's time using the latest technology to find out more about their state of health, what diseases they were suffering from and the nature of their deaths.

    "We hope in the future to image the soft tissues at the cellular level to look at whether there's any changes or to find evidence, for example, of cardiovascular diseases but also things like cancer."

    The scans found that one of mummies, Tamut, a priest's daughter from about 900BC, had plaque in her arteries. Three-dimensional printing was also used to recreate amulets found during scans of her mummified remains.

    The earliest evidence of mummification in Egypt suggests that the practice of wrapping bodies to preserve them after death dates back as far as 4500BC.

    The mummies are due to travel to Asia next year.

    Source: AFP [December 08, 2016]

  • Earth Science: New evidence found of land and ocean responses to climate change over last millennium

    Earth Science: New evidence found of land and ocean responses to climate change over last millennium

    A multidisciplinary research team including University of Granada (UGR) researchers has analyzed two sea bed loggings retrieved from the Alboran Sea's basin at very high resolution and reconstructed climate and oceanographic conditions over the last millennium, including the anthropogenic influence in the westernmost region of the Mediterranean Sea.

    New evidence found of land and ocean responses to climate change over last millennium
    Two sea bed loggings from the Alboran Sea have been analyzed at very high resolution and have allowed to
     reconstruct climate and oceanographic conditions as well as anthropogenic influence in the westernmost 
    region of the Mediterranean Sea over that period [Credit: UGRdivulga]

    Global warming, climate change and their effects on health and safety are probably the worst threats in mankind's history. Recent reports from the Intergovernmental Panel on Climate Change (IPCC 2007, 2014) have accumulated scientific evidence that the observed rise in mean ground temperature all over the world from the beginning of the 20th century is probably due to anthropogenic influence.

    Moreover, global mean concentration of carbon dioxide in the atmosphere has risen since the industrial revolution due to human activities. This concentration has surpassed that found in ice cores over the last 800 000 years. In January 2016, NASA and the U.S. National Oceanic and Atmospheric Administration (NOAA) revealed that global mean temperature in 2015 was the highest since 1880, when records began.

    Reconstructions of the global ground temperature in the Northern Hemisphere over the last millennium show hotter conditions during the so called Medieval Climatic Anomaly (800-1300 A.C.) and cooler temperatures during the Little Ice Age (1300-1850 A.C.).

    Natural climate variability

    Climate models give us a coherent explanation of the progressive cooling over the last millennium due to a natural climate variability (solar cycle changes and volcanic eruptions). However, we can see that this global tendency has reverted during the 20th century. Climate models are not capable of simulating the fast warming observed during the last century without including human impact along with natural mechanisms of climate forcing.

    With this in mind, a multidisciplinary team of researchers has conducted a study reconstructing climate and oceanographic conditions in the westernmost region of the Mediterranean Sea. For that purpose, they have used marine sediments retrieved from the Alboran Sea's basin.

    As a semi-closed basin located in a latitude affected by several climate types, it's especially sensitive and vulnerable to anthropogenic and climate forcing. Several organic and inorganic geochemical indicators have been integrated in the model for this research, thus deducing climate variables such as sea surface temperature, humidity, changes in vegetation cover, changes in sea currents, and human impact.

    These indicators have shown consistent climate signals in the two sea bed loggings—essentially hot and dry climate conditions during the Medieval Climatic Anomaly, which switched to mostly cold and wet conditions during the Little Ice Age. The industrial period showed wetter conditions than during the Little Ice Age, and the second half of the 20th century has been characterized by an increasing aridity.

    Climate variability in the Mediterranean region seems to be driven by variations in solar irradiation and changes in the North Atlantic Oscillation (NAO) during the last millennium. The NAO alternates a positive phase with a negative one. The positive phase is characterized by western winds, which are more intense and move storms towards northern Europe, which resulted in dry winters in the Mediterranean region and the north of Africa during the Medieval Climatic Anomaly and the second half of the 20th century.

    In contrast, the negative phase is associated with opposite conditions during the Little Ice Age and the industrial period. Our records show that during NAO prolonged negative phases (1450 and 1950 A.C.), there occurred a weakening of the thermohaline circulation and a reduction of "upwelling" events (emergence of colder, more nutrient-rich waters). Anthropogenic influence shows up in the unprecedented increase of temperature, progressive aridification and soil erosion, and an increase of polluting elements since the industrial period. On a broad scale, atmospheric circulation patterns, oceanic circulation patterns (the NAO and the Atlantic meridional overturning circulation), and variations in solar irradiance seem to have played a key role during the last millennium.

    Results show that recent climate records in the westernmost region of the Mediterranean Sea are caused by natural forcing and anthropogenic influence. The main conclusions derived from this research have been published in a special volume of the >Journal of the Geological Society of London about climate change during the Holocene.

    Source: University of Granada [October 12, 2016]

  • Genetics: Scientists sequence ancient British 'gladiator' genomes from Roman York

    Genetics: Scientists sequence ancient British 'gladiator' genomes from Roman York

    Cutting-edge genome technology in Trinity College Dublin has cast more light on a mystery that has perplexed archaeologists for more than a decade. The origins of a set of Roman-age decapitated bodies, found by York Archaeological Trust at Driffield Terrace in the city, have been explored, revealing a Middle Eastern body alongside native British.

    Scientists sequence ancient British 'gladiator' genomes from Roman York
    One of the skeletons excavated by York Archaeological Trust at Driffield Terrace
    [Credit: York Archaeological Trust]

    Archaeologists have speculated that the skeletons belonged to gladiators, although they could also have been soldiers or criminals. Several suffered perimortem decapitation and were all of a similar age – under 45 years old. Their skulls were buried with the body, although not positioned consistently – some were on the chest, some within the legs, and others at the feet.

    Although examining the skeletons revealed much about the life they lived – including childhood deprivation and injuries consistent with battle trauma – it was not until genomic analysis by a team from Trinity College Dublin, led by Professor of Population Genetics, Dan Bradley, that archaeologists could start to piece together the origins of the men.

    The Trinity College team recently published the first prehistoric Irish genomes and this analysis by Trinity PhD Researcher, Rui Martiniano, also breaks new ground as it represents the first genome analysis of ancient Britons.

    From the skeletons of more than 80 individuals, Dr Gundula Muldner of the University of Reading, Dr Janet Montgomery of the University of Durham and Malin Holst and Anwen Caffel of York Osteoarchaeology selected seven for whole genome analyses. Despite variation in isotope levels which suggested some of the 80 individuals lived their early lives outside Britain, most of those sampled had genomes similar to an earlier Iron Age woman from Melton, East Yorkshire. The poor childhood health of these men suggests that they were locals who endured childhood stress, but their robust skeletons and healed trauma, suggest that they were used to wielding weapons.

    Scientists sequence ancient British 'gladiator' genomes from Roman York
    The Roman-age skeletons from Driffield Terrace laid out in York's Guildhall 
    [Credit: York Archaeological Trust]

    The nearest modern descendants of the Roman British men sampled live not in Yorkshire, but in Wales. A man from a Christian Anglo-Saxon cemetery in the village of Norton, Teesside, has genes more closely aligned to modern East Anglia and Dutch individuals and highlights the impact of later migrations upon the genetic makeup of the earlier Roman British inhabitants.

    However, one of the decapitated Romans had a very different story, of Middle Eastern origin he grew up in the region of modern day Palestine, Jordan or Syria before migrating to this region and meeting his death in York.

    "Archaeology and osteoarchaeology can tell us a certain amount about the skeletons, but this new genomic and isotopic research can not only tell us about the body we see, but about its origins, and that is a huge step forward in understanding populations, migration patterns and how people moved around the ancient world," says Christine McDonnell, Head of Curatorial and Archive Services for York Archaeological Trust.

    "This hugely exciting, pioneering work will become the new standard for understanding the origins of skeletons in the future, and as the field grows, and costs of undertaking this kind of investigation fall, we may be able to refine our knowledge of exactly where the bodies were born to a much smaller region. That is a remarkable advance."

    Scientists sequence ancient British 'gladiator' genomes from Roman York
    The Roman skeletons were found at Driffield Terrace in York with their skulls placed between their legs,
     at their feet or on their chests [Credit: York Archaeological Trust]

    As well as Trinity College Dublin, the multi-disciplinary scientific analysis involved scientists from the University of York and The York Archaeological Trust, as well as the universities of Durham, Reading and Sheffield, University College London and the University Medical Centre in Utrecht. The research also included experts from York Osteoarchaeology Ltd, City of York Council and the Natural History Museum.

    The Roman skeletons sampled were all male, under 45 years old and most had evidence of decapitation. They were taller than average for Roman Britain and displayed evidence of significant trauma potentially related to interpersonal violence. All but one would have had brown eyes and black or brown hair but one had distinctive blue eyes and blond hair similar to the single Anglo-Saxon individual.

    The demographic profile of the York skeletons resembles the population structure in a Roman burial ground believed to be for gladiators at Ephesus. But the evidence could also fit with a military context—the Roman army had a minimum recruitment height and fallen soldiers would match the age profile of the York cemetery.

    Professor Dan Bradley, Trinity, said: "Whichever the identity of the enigmatic headless Romans from York, our sample of the genomes of seven of them, when combined with isotopic evidence, indicate six to be of British origin and one to have origins in the Middle East. It confirms the cosmopolitan character of the Roman Empire even at its most northerly extent."

    PhD Researcher and lead author, Rui Martiniano, Trinity, said: "This is the first refined genomic evidence for far-reaching ancient mobility and also the first snapshot of British genomes in the early centuries AD, indicating continuity with an Iron Age sample before the migrations of the Anglo-Saxon period."

    Professor Matthew Collins, of the BioArCh research facility in the Department of Archaeology at York, who co-ordinated the report on the research, "These genomes give the first snapshot of British genomes in the early centuries AD, showing continuity with the earlier Iron Age and evidence of migrations in the Anglo-Saxon period."

    The paper is published in >Nature Communications.

    Source: Trinity College Dublin [January 20, 2016]

  • Oceans: Almost all seabirds to have plastic in gut by 2050

    Oceans: Almost all seabirds to have plastic in gut by 2050

    Researchers from CSIRO and Imperial College London have assessed how widespread the threat of plastic is for the world's seabirds, including albatrosses, shearwaters and penguins, and found the majority of seabird species have plastic in their gut.

    Almost all seabirds to have plastic in gut by 2050
    A red-footed booby on Christmas Island [Credit: CSIRO]

    The study, led by Dr Chris Wilcox with co-authors Dr Denise Hardesty and Dr Erik van Sebille and published today in the journal PNAS, found that nearly 60 per cent of all seabird species have plastic in their gut.

    Based on analysis of published studies since the early 1960s, the researchers found that plastic is increasingly common in seabird's stomachs.

    In 1960, plastic was found in the stomach of less than 5 per cent of individual seabirds, rising to 80 per cent by 2010.

    The researchers predict that plastic ingestion will affect 99 per cent of the world's seabird species by 2050, based on current trends.

    The scientists estimate that 90 per cent of all seabirds alive today have eaten plastic of some kind.

    This includes bags, bottle caps, and plastic fibres from synthetic clothes, which have washed out into the ocean from urban rivers, sewers and waste deposits.

    Birds mistake the brightly coloured items for food, or swallow them by accident, and this causes gut impaction, weight loss and sometimes even death.

    "For the first time, we have a global prediction of how wide-reaching plastic impacts may be on marine species -- and the results are striking," senior research scientist at CSIRO Oceans and Atmosphere Dr Wilcox said.

    "We predict, using historical observations, that 90 per cent of individual seabirds have eaten plastic. This is a huge amount and really points to the ubiquity of plastic pollution."

    Dr Denise Hardesty from CSIRO Oceans and Atmosphere said seabirds were excellent indicators of ecosystem health.

    "Finding such widespread estimates of plastic in seabirds is borne out by some of the fieldwork we've carried out where I've found nearly 200 pieces of plastic in a single seabird," Dr Hardesty said.

    The researchers found plastics will have the greatest impact on wildlife where they gather in the Southern Ocean, in a band around the southern edges of Australia, South Africa and South America.

    Dr van Sebille, from the Grantham Institute at Imperial College London, said the plastics had the most devastating impact in the areas where there was the greatest diversity of species.

    "We are very concerned about species such as penguins and giant albatrosses, which live in these areas," Erik van Sebille said.

    "While the infamous garbage patches in the middle of the oceans have strikingly high densities of plastic, very few animals live here."

    Dr Hardesty said there was still the opportunity to change the impact plastic had on seabirds.

    "Improving waste management can reduce the threat plastic is posing to marine wildlife," she said.

    "Even simple measures can make a difference. Efforts to reduce plastics losses into the environment in Europe resulted in measureable changes in plastic in seabird stomachs with less than a decade, which suggests that improvements in basic waste management can reduce plastic in the environment in a really short time."

    Chief Scientist at the US-based Ocean Conservancy Dr George H. Leonard said the study was highly important and demonstrated how pervasive plastics were in oceans.

    "Hundreds of thousands of volunteers around the world come face-to-face with this problem during annual Coastal Cleanup events," Dr Leonard said.

    "Scientists, the private sector and global citizens working together against the growing onslaught of plastic pollution can reduce plastic inputs to help protect marine biodiversity."

    Source: CSIRO Australia [September 01, 2015]

  • UK: Discovery of rare Anglo-Saxon burials is revealed

    UK: Discovery of rare Anglo-Saxon burials is revealed

    Archaeologists have uncovered an important Anglo-Saxon cemetery in an excavation in advance of a conservation and fishing lake and flood defence system at Great Ryburgh in Norfolk. The waterlogged conditions of the river valley led to the remarkable preservation of burials that are extremely rare in the archaeological record, including plank-lined graves and tree-trunk coffins dating from the 7th-9th century AD.

    Discovery of rare Anglo-Saxon burials is revealed
    Aerial view of the excavation of an Anglo Saxon cemetery at Great Ryburgh 
    [Credit: (c) MOLA]

    It is believed that this may have been the final resting place for a community of early Christians including a timber structure thought to be a church or chapel, of which there are few examples from this period. The wooden grave markers, east-west alignment of the coffins and the evident lack of grave goods all support the Christian origins of the cemetery.

    Anglo-Saxon coffins seldom survive because wood decays over time. Until now, evidence of these amazing burials has largely consisted of staining in the ground from decayed wood, but archaeologists have been able to properly excavate these rare and fascinating coffins, graves and skeletons because they have been brilliantly preserved in the ground in a combination of acidic sand and alkaline water.

    Discovery of rare Anglo-Saxon burials is revealed
    MOLA archaeologist excavates human remains at great Ryburgh 
    [Credit: (c) MOLA]

    The 81 dug-out coffins discovered comprise oak trees split in two length-ways and hollowed out. This type of coffin is first seen in Europe in the Early Bronze Age and reappears in the early medieval period. From Britain they are mentioned in antiquarian records from the late 19th century, but this is the very first time they have been properly excavated and recorded by modern archaeologists.

    We know that the burials, in hollowed out logs, were positioned in the lower half and the upper half rested on top to form a lid. Although they aren’t decorative, it would have taken considerable effort to hollow a single coffin, an estimated four man days. The fact that evidence for similar burial rites is also found in earlier cemeteries may signify the blending of pagan and Christian traditions.

    Discovery of rare Anglo-Saxon burials is revealed
    An archaeologist records human remains at Great Ryburgh 
    [Credit: (c) MOLA]

    The six plank-lined graves are very rare in in this country and these are believed to be the earliest known examples from Britain. The graves were cut into the ground, lined with expertly hewn timber planks, the body placed inside and planks positioned on top to form a cover.

    The relationship between the two burial types is not fully understood, but may denote an evolution in burial practices. Tree-ring dating is being undertaken to date the timber. The discovery is shedding light on a previously unknown religious site and the fascinating lives of this early Christian rural community.

    Middle Saxon burial with wooden coffin by MOLA on Sketchfab
    Continued research and scientific testing, in the form of ancient DNA, stable isotope and dental calculus analysis, will help to develop biographies for the people buried and paint a picture of the people who lived here.

    Archaeologists hope to be able to say more about where these people came from, whether they were related, and what their diet and health were like, once research is complete.

    Source: Museum of London Archaeology [November 16, 2016]

  • Turkey: Early farmers from across Europe were direct descendants of Aegeans

    Turkey: Early farmers from across Europe were direct descendants of Aegeans

    For most of the last 45,000 years Europe was inhabited solely by hunter-gatherers. About 8,500 years ago a new form of subsistence -- farming -- started to spread across the continent from modern-day Turkey, reaching central Europe by 7,500 years ago and Britain by 6,100 years ago. This new subsistence strategy led to profound changes in society, including greater population density, new diseases, and poorer health. Such was the impact of farming on how we live that scientists have debated for more than 100 years how it was spread across Europe. Many believed that farming was spread as an idea to European hunter-gatherers but without a major migration of farmers themselves.

    Early farmers from across Europe were direct descendants of Aegeans
    Human skeleton from an archaeological excavation in northern Greece, from where 
    one neolithic genome originates [Credit: ©: K. Kotsakis and P. Halstead, 
    Paliambela Excavation Project Archive]

    This week, an international research team led by paleogeneticists of Johannes Gutenberg University Mainz (JGU) publishes a study in the journal >Proceedings of the National Academy of Sciences showing that early farmers from across Europe have an almost unbroken trail of ancestry leading back to the Aegean.

    The scientists analyzed the DNA of early farmer skeletons from Greece and Turkey. According to the study, the Neolithic settlers from northern Greece and the Marmara Sea region of western Turkey reached central Europe via a Balkan route and the Iberian Peninsula via a Mediterranean route. These colonists brought sedentary life, agriculture, and domestic animals and plants to Europe.

    During their expansion they will have met hunter-gatherers who lived in Europe since the Ice Age, but the two groups mixed initially only to a very limited extent. "They exchanged cultural heritage and knowledge, but rarely spouses," commented anthropologist Joachim Burger, who lead the research. "Only after centuries did the number of partnerships increase."

    Professor Joachim Burger, his Mainz paleogeneticist team, and international collaborators have pioneered paleogenetic research of the Neolithization process in Europe over the last seven years.

    Early farmers from across Europe were direct descendants of Aegeans
    View of the ancient DNA trace laboratory [Credit: ©: AG Palaeogenetik, JGU]

    They showed a lack of interbreeding between farmers and hunter-gatherers in prehistoric Europe in 2009 and 2013 (Bramanti et al. 2009; Bollongino et al. 2013). Now, they demonstrate that the cultural and genetic differences were the result of separate geographical origins.

    "The migrating farmers did not only bring a completely foreign culture, but looked different and spoke a different language," stated Christina Papageorgopoulou from Democritus University of Thrace, Greece,, who initiated the study as a Humboldt Fellow in Mainz together with Joachim Burger.

    The study used genomic analysis to clarify a long-standing debate about the origins of the first European farmers by showing that the ancestry of Central and Southwestern Europeans can be traced directly back to Greece and northwestern Anatolia.

    "There are still details to flesh out, and no doubt there will be surprises around the corner, but when it comes to the big picture on how farming spread into Europe, this debate is over," said Mark Thomas of University College London (UCL), co-author on the study. "Thanks to ancient DNA, our understanding of the Neolithic revolution has fundamentally changed over the last seven years."

    Sedentary life, farming, and animal husbandry were already present 10,000 years ago in the so-called Fertile Crescent, a region covering modern-day Turkey, Syria, Iran, and Iraq. Zuzana Hofmanová and Susanne Kreutzer, the lead authors of the study, concluded: "Whether the first farmers came ultimately from this area is not yet established, but certainly we have seen with our study that these people, together with their revolutionary Neolithic culture, colonized Europe through northern Aegean over a short period of time."

    Another study has shown that the spread of farming, and farmers, was not the last major migration to Europe. Approximately 5,000 years ago people of the eastern Steppe reached Central Europe and mixed with the former hunter-gatherers and early farmers. The majority of current European populations arose as a mixture of these three groups.

    Source: Johannes Gutenberg Universitaet Mainz [June 06, 2016]

  • Natural Heritage: Global wildlife populations decline by 58 percent

    Natural Heritage: Global wildlife populations decline by 58 percent

    Global populations of vertebrates -- mammals, birds, reptiles, amphibians, and fish -- have declined by 58 percent between 1970 and 2012, states a new report from World Wildlife Fund (WWF). Animals living in the world's lakes, rivers, and freshwater systems have experienced the most dramatic population declines, at 81 percent. Because of human activity, the report states that without immediate intervention global wildlife populations could drop two-thirds by 2020.

    Global wildlife populations decline by 58 percent
    Jaguar [Credit: © Barry Draper]

    "This research delivers a wake-up call that for decades we've treated our planet as if it's disposable," said Carter Roberts, WWF president and CEO. "We created this problem. The good news is that we can fix it. It requires updating our approach to food, energy, transportation, and how we live our lives. We share the same planet. We rely on it for our survival. So we are all responsible for its protection."

    The top threat to wildlife is habitat loss and degradation, driven primarily by increasing demand for food and energy. According to the report, global food production is the leading cause for destruction of habitats and overexploitation of wildlife. Agriculture currently occupies approximately one-third of Earth's total land area and accounts for 70 percent of all freshwater use.

    Wild animals are not the only ones at risk; the report states that increased pressure threatens the natural resources that all life -- including humanity -- depend on.


    The report demonstrates the need to rethink how we produce, consume, measure success and value the natural environment, and calls for an urgent system change by individuals, businesses and governments. The report also illustrates the positive momentum that is building by highlighting recent global agreements on climate change and sustainable development. In particular, the report recognizes the 2030 Agenda for Sustainable Development as an essential guide to decision-making that can ensure that the environment is valued alongside economic and social interests.

    "A strong natural environment is the key to defeating poverty, improving health and developing a just and prosperous future," said Marco Lambertini, WWF director general. "We have proven that we know what it takes to build a resilient planet for future generations, we just need to act on that knowledge."

    >Living Planet Report 2016: Risk and resilience in a new era is the eleventh edition of WWF's biennial flagship publication. The report tracks over 14,000 vertebrate populations of over 3,700 species from 1970 to 2012 and includes research from the Global Footprint Network and the Zoological Society of London.

    Source: World Wildlife Fund [October 27, 2016]

  • Genetics: Obesity in humans linked to fat gene in prehistoric apes

    Genetics: Obesity in humans linked to fat gene in prehistoric apes

    A genetic mutation in extinct European apes that enabled them to convert fruit sugar into fat could be a cause of the modern obesity epidemic and diabetes, according to scientists. Fossil evidence reveals that apes living around 16 million years ago, in what was then subtropical Europe, began to suffer as global cooling subsequently changed the forest, making the fruit they ate scarce.

    Obesity in humans linked to fat gene in prehistoric apes
    Extinct European apes evolved into today's great apes and the earliest hominids 
    [Credit: Nathan Thompson, Lucille Betti-Nash, and Deming Yang]

    Experts suggest that a mutation in the uricase gene which helps to convert fruit sugar (fructose) occurred around 15 million years ago. This aided apes in adding on fat layers so they could survive famines and harsh winters.

    Persistence of the same mutation in all modern great apes and all modern humans, along with the fossil evidence, suggests that the now extinct European apes evolved into today's great apes and the earliest hominids.

    Scientists have spent decades researching the genetic causes of obesity which is rarely found in other animals – apart from domesticated pets. The latest research focuses on fructose: a sugar which breaks down to form uric acid in the blood, according to a Sunday Times report.

    The Western diet contains so much uric acid that it cannot be removed quickly enough, but triggers liver cells to turn fructose into fat, with the effect of humans adding on extra weight. The uricase mutation predisposes humans to obesity and diabetes in modern times. The results suggest a need to eat and drink much less fructose to fight obesity and prevent its dangerous complications.

    "The gene enables uric acid levels to spike in response to two types of food," wrote Peter Andrews, professor of anthropology at University College London in Scientific American, co-authored with Richard Johnson, a professor of medicine in the US. "Those like beer that produce a lot of uric acid [directly] and those that contain a lot of fructose. These include honey and processed food that are high in table sugar or high-fructose corn syrup. When uric acid spikes we become susceptible to obesity and diabetes."

    Obesity is considered as one of the biggest public health challenges of the century. Statistics show that it is affecting more than 500 million people worldwide. In the US alone, obesity costs at least $200 billion each year.

    This medical condition also contributes to potentially fatal disorders such as cancer, type 2 diabetes and cardiovascular disease.

    Author: Fiona Keating | Source: International Business Times [November 20, 2015]

  • Greenland: What the Inuit can tell us about omega-3 fats and ‘paleo’ diets

    Greenland: What the Inuit can tell us about omega-3 fats and ‘paleo’ diets

    The traditional diet of Greenland natives — the Inuit — is held up as an example of how high levels of omega-3 fatty acids can counterbalance the bad health effects of a high-fat diet, but a new study hints that what’s true for the Inuit may not be true for everyone else.

    What the Inuit can tell us about omega-3 fats and ‘paleo’ diets
    A village on the coast of Greenland, where the native Inuit population traditionally 
    ate diets high in omega-3 fats. Over thousands of years, they developed genetic
     mutations that allowed them to remain healthy despite the fatty diet, but this
     adaptation had other consequences, such as short height 
    [Credit: Malik Milfeldt]

    The study, which appears in the Sept. 18 issue of the journal Science, shows that the Inuit and their Siberian ancestors have special mutations in genes involved in fat metabolism. The mutations help them partly counteract the effects of a diet high in marine mammal fat, mostly from seals and whales that eat fish with high levels of omega-3 polyunsaturated fatty acids.

    Those genetic mutations, found in nearly 100 percent of the Inuit, are found in a mere 2 percent of Europeans and 15 percent of Han Chinese, which means that these groups would synthesize omega-3 polyunsaturated fatty acids differently from the Inuit.

    “The original focus on fish oil and omega-3s came from studies of Inuit. On their traditional diet, rich in fat from marine mammals, Inuit seemed quite healthy with a low incidence of cardiovascular disease, so fish oil must be protective,” said project leader Rasmus Nielsen, a UC Berkeley professor of integrative biology. “We’ve now found that they have unique genetic adaptations to this diet, so you cannot extrapolate from them to other populations. A diet that is healthy for the Inuit may not necessarily be good for the rest of us.”

    These genetic mutations in the Inuit have more widespread effects. They lower “bad” LDL cholesterol and fasting insulin levels, presumably protecting against cardiovascular disease and diabetes. They also have a significant effect on height, because growth is in part regulated by a person’s fatty acid profile. The researchers found that the mutations causing shorter height in the Inuit are also associated with shorter height in Europeans.

    “The mutations we found in the Inuit have profound physiological effects, changing the whole profile of fatty acids in the body, plus it reduces their height by 2 centimeters: nearly an inch,” said Ida Moltke, a University of Copenhagen associate professor of bioinformatics who is joint first author on the study. “Height is controlled by many genes, but this mutation has one of the strongest effects on height ever found by geneticists.”

    Personalized diets

    Nielsen noted that this is some of the clearest evidence to date that human populations are actually adapted to particular diets; that is, they differ in the way they physiologically respond to diets. Just as genome sequencing can lead to personalized medicine tailored to an individual’s specific set of genes, so too may a person’s genome dictate a personalized diet.

    What the Inuit can tell us about omega-3 fats and ‘paleo’ diets
    Seals and walruses were part of the traditional diet of the Inuit, as seen in this
     illustration of a native village on Canada’s Baffin Island, from the book Arctic 
    Researches and Life Among the Esquimaux (1865) by Charles Francis Hall 
    [Credit: University of California, Berkeley]

    “People ask themselves whether they should be on a Stone Age diet, for example. The response may well depend on their genome,” Nielsen said.

    Nielsen and his colleagues at UC Berkeley and in Greenland and Denmark came to their conclusions after analyzing the genomes of 191 Greenlanders with a low admixture of European genes (less than 5 percent) and comparing them to the genomes of 60 Europeans and 44 Han Chinese. They looked for mutations occurring in a large percentage of Inuit individuals but in few or no other groups, which indicates that the mutation spread throughout the Inuit because it was somehow useful to their survival while not essential in other groups.

    One cluster of mutations — in genes that code for enzymes that desaturate carbon-carbon bonds in fatty acids — stood out strongly, said Anders Albrechtsen, an associate professor of bioinformatics at the University of Copenhagen and a joint project leader. Fatty acids are the fat in our diet, and occur in saturated, polyunsaturated and unsaturated forms, depending on whether the molecules’ carbon atoms are linked together with no, some or all double bonds. Saturated fats are considered bad because they raise levels of cholesterol in the blood and lower the “good” high-density lipoproteins (HDL), all of which leads to plaque formation and clogged arteries. Diets rich in polyunsaturated and unsaturated fats are linked to lower heart disease. Desaturase enzymes convert dietary fatty acids into fatty acids stored and metabolized by the body.

    The mutations common in the Inuit, once known as Eskimos, decrease the production of both omega-3 and omega-6 polyunsaturated fatty acids, presumably to account for the high amount of these fatty acids coming from the diet. Changing production of one fatty acid affects all fatty acids, however, since they regulate one another in a complex way, Albrechtsen said.

    Thus, while it’s not clear which specific gene or genes within the cluster is responsible for the alteration in fatty acid metabolism, he said that “when you change the genes that are involved in fatty acid synthesis, you change the whole conversation among fatty acids, and that has a lot of downstream effects.”

    Adaptation to Ice Age living

    The mutations seem to be at least 20,000 years old, and may have helped many groups of humans adapt to high-meat, high-fat, hunter-gatherer diets from large land and marine mammals high in certain types of omega-3 and omega-6 fatty acids, said Matteo Fumagalli, a researcher at University College London, who is joint first author of the study. They may have arisen among the original Siberians, who have lived in the Arctic for more than 20,000 years and arrived in Greenland when Inuit settled there about 1,000 years ago.

    “We think it is a quite old selection that may have helped humans adapt to the environment during the last Ice Age, but the selection is far stronger in the Inuit than anywhere else,” said Fumagalli. “It’s fascinating that Greenlanders have a unique genetic makeup that lets them better use their traditional food sources.”

    The researchers discovered another common mutation in a gene that is involved in the differentiation of brown, subcutaneous fat cells and brite fat cells, the latter of which generate heat. This may also have helped the Inuit adapt to a cold environment.

    Author: Robert Sanders | Source: University of California, Berkeley [September 18, 2015]

  • UK: Rare discovery of Late Roman official buried in Leicester

    UK: Rare discovery of Late Roman official buried in Leicester

    Archaeologists from University of Leicester Archaeological Services (ULAS) have recently excavated a Late Roman cemetery at Western Road in Leicester’s West End. Amongst the 83 skeletons recorded by the team, one burial is proving to be very exciting.

    Rare discovery of Late Roman official buried in Leicester
    An archaeologist excavates one of the skeletons in the Roman cemetery at Western Road 
    [Credit: University of Leicester]

    The simple grave in question had been dug into mudstone on the west bank of the River Soar, to the south-west of the Roman town close to the important road known as the Fosse Way. Buried in the grave was the remains of a middle-aged man wearing an elaborately decorated belt in a style that would have been worn by a Late Roman soldier or civil servant during the second half of the 4th century or the early 5th century AD.

    The find, which is rare in Britain, was positioned at the waist of the skeleton and comprises a belt buckle, belt plate and strap end.

    Rare discovery of Late Roman official buried in Leicester
    The grave of Skeleton 23, thought to be a late Roman soldier or civil servant. The belt buckle was 
    found next to the right hip (circled) [Credit: University of Leicester]

    Nick Cooper, Post-Excavation Manager at ULAS, said: “The survival of the delicate thin sheet bronze belt plate is remarkable. It is cast in the so-called ‘chip-carved’ style decorated with interlocking spirals and would have been riveted to a wide leather belt or girdle with a thinner securing strap running through the buckle and ending with the strap end.”

    The buckle is decorated with dolphin heads and the strap end is decorated with crouching dogs on either side of its tapered end.

    Rare discovery of Late Roman official buried in Leicester
    The belt buckle is decorated with dolphin heads 
    [Credit: University of Leicester]

    Parallels for this belt set have been found in other Late Roman cemeteries, for example in London, Dorchester on Thames and Winchester, and at the shore fort on the opposite side of the English Channel at Oudenburg in Belgium.

    Research shows that these belts were worn across north-eastern France, Belgium, and along the eastern frontier of the Roman Empire, running along the Rivers Rhine and Danube, where soldiers were stationed. There is some contemporary pictorial evidence to suggest that this type, specifically, was worn by members of the Late Roman military and civilian elite and that the belts were important symbols of authority.

    Rare discovery of Late Roman official buried in Leicester
    The strap end is decorated with crouching dogs on either side of its tapered end 
    [Credit: University of Leicester]

    The recent discovery at Western Road is the first occurrence of such a complex belt set in Roman Leicester. The belt’s owner was aged between 36 and 45 when he died. He had survived poor health in childhood to lead a comparatively fit adult life but at some point he had fractured his left forearm; an injury that had healed well but left his wrist weakened. This type of injury is known as a ‘parry fracture’ and is typically caused by raising the arm to ward off a blow or a falling object. The man had also damaged muscles in his upper right arm and shoulder. Such injuries could possibly be caused by over-use, overextending the muscles with movements such as throwing and lifting. Whilst it is difficult to identify exactly what caused these injuries, they are consistent with those a soldier might suffer and reinforce the theory that this man was either a member of the late Roman army or, perhaps following retirement, became an important local civil servant.

    Rare discovery of Late Roman official buried in Leicester
    The bronze belt plate is cast in the so-called ‘chip-carved’ style and would have been riveted to a wide leather
     belt or girdle with a thinner securing strap running through the buckle and ending with the strap end 
    [Credit: University of Leicester]

    The project is funded by Jamie Lewis Residential as part of the site’s redevelopment. Excavation and analysis of the skeletal assemblage has been carried out by a multi-disciplinary team of researchers from University of Leicester Archaeological Services (ULAS), York Osteoarchaeology Ltd., the Scottish Universities Environmental Research Centre (SUERC) and the British Geological Survey (BGS). The belt has been conserved by Graham Morgan.

    The belt buckle and other finds from the excavation will be on display on Sunday 10 July at ‘Bringing Our Past To Life’, an exciting family friendly heritage day at Jewry Wall Museum, Leicester (11am-4pm).

    Source: University of Leicester [July 07, 2016]

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